Premotor Cortical Areas with Increased BOLD Responses with Both the Left- and the Right-Hand Map Overlaid on Coronal Slices of the MNI T1-Weighted Brain Template

<p>For the left hemisphere (L), significant activations ( <i>p</i> < 0.01, FWE-corrected) occurred in one cluster (443 voxels) with two maxima in precentral gyrus (#2 and #4; BA 6), in one single-peak cluster (153 voxels) in superior frontal gyrus (#3; BA 6), in one cluster (281 voxels) with two maxima in medial frontal gyrus (#5 and #6; BA 6), and in one small single-peak cluster (29 voxels) in left inferior frontal gyrus (#1; BA 44). In the right hemisphere (R), there was one cluster (303 voxels) with three maxima, one of which was located in the precentral gyrus outside the cluster delineated by left-hand-map > right-hand-map contrast (#7; BA 6). Solid black lines in the left and right hemisphere outline the clusters identified with the right-hand-map > left-hand-map and left-hand-map > right-hand-map contrasts, respectively (see <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0040158#pbio-0040158-g004" target="_blank">Figure 4</a>C). Histograms give percent BOLD signal change relative to mean of session for the local maxima of identified clusters. Red and blue columns refer to left- and right-hand maps, respectively. Column height gives data averaged across participants and error bar ± 1SEM ( <i>n</i> = 16). Coordinates (X, Y, Z in MNI stereotaxic space) and <i>t</i>₍₃₀₎ values for the maxima are presented below each histogram.