Post-Training Modulation of Neuronal Activity and Behavioral Performance

<div><p>(A) Activations are superimposed on one participant's T1-weighted normalized MRI image. Left side: Plots of the correlation between changes in spatial performance (distance left to target in learning minus test sessions) and brain response during intervening oddball Session II (versus I; [B]) in the hippocampus ([24 −24 −2 mm], Z = 3.75, <i>p</i>^svc(10mm) < 0.05) around an a priori location [26 −24 −8 mm]). Each point represents one participant. Part C shows the non-significant correlation ( <i>p</i> > 0.8) at the same location during Session III (versus II). Right side: Plots of the correlation between individual levels of sequence knowledge (RT for novel minus learned sequence) at the end of the Learning phase and brain response during (B) Session II (versus I), showing the non-significant correlation in the left caudate nucleus, and (C) intervening oddball Session III (versus II[C]) in the same location ([−12 −2 20 mm], Z = 4.48, <i>p</i>^svc < 0.005). </p> <p> <i>r</i> = correlation coefficient. </p>