Outcome of visceral infection in UCP2KO and WT C57BL/6 mice.

<p>All mice were challenged intravenously with 5×10⁵ live, stationary-phase <i>L. infantum</i> parasites, and spleens, livers and sera were harvested at 8 weeks after infection. A. UCP2KO mice reduce parasite loads (assessed by limiting dilution) in spleen and liver more efficiently than WT mice. B. Anti-SLA antibody (IgG1 and IgG2a) titers were determined by ELISA. Data are presented as mean ± S.D. (n = 6). Asterisks indicate <i>P</i><0.05 with respect to WT mice.