<div><p>(A) Northern blots indicate that siRNA levels are further increased in the 8/26 bigenic mice.</p><p>(B) Western blots demonstrate that SOD2 protein levels are further knocked down in the 8/26 bigenic mice.</p><p>(C) Real-time PCR shows that SOD2 mRNA levels are further lowered in the 8/26 bigenic mice.</p></div
<p>Total RNA extracted from brains of TgMHu2ME199K (tg), PrP <sup>0/0</sup> (ko) and wt mice, od des...
RNA interference (RNAi) has been used increasingly for reverse genetics in invertebrates and mammali...
<p>(A) Western blot analysis of GPx in the liver of the same control and HBV transgenic mice as desc...
<div><p>(A) Histochemical staining reveals that SDH activity in the heart of transgenic line-8 mice ...
<div><p>(A) Schematic illustration of the transgene construct. The shRNA was designed to mimic human...
<p>(A) Genotyping of the SOD-1 (G93A)<sup>PS</sup> mouse reveals a characteristic band from the SOD-...
Prion diseases are progressive, neurodegenerative diseases affecting humans and animals. Also known ...
<p>The temporal mRNA expression profiles of M1 [CD86 (A), IL-1β (B), TNF-α (C) and NOX2 (D)] and M2 ...
<p>The log<sub>2</sub> transformation of the fold-change of the relative mRNA expression levels in t...
<p>A, expression of <i>Soat1</i> protein in transgenic mice. PC, positive control: lane loaded with ...
<p>Panel A and B. Quantification of <i>Sod1</i> mRNA expression in whole brain by real-time RT-PCR. ...
<p>(A) Semi-quantitative RT-PCR analysis confirmed that the identified mRNA species by DNA microarra...
Approximately 10 % of amyotrophic lateral sclerosis (ALS) cases are familial (FALS), and 25 % of FAL...
AbstractIn short hairpin RNA (shRNA) transgenic mice, the tissue difference in gene silencing effici...
<p>(A) Representative data for western blot analysis of the human mutant SOD1 proteins (hSOD1). The ...
<p>Total RNA extracted from brains of TgMHu2ME199K (tg), PrP <sup>0/0</sup> (ko) and wt mice, od des...
RNA interference (RNAi) has been used increasingly for reverse genetics in invertebrates and mammali...
<p>(A) Western blot analysis of GPx in the liver of the same control and HBV transgenic mice as desc...
<div><p>(A) Histochemical staining reveals that SDH activity in the heart of transgenic line-8 mice ...
<div><p>(A) Schematic illustration of the transgene construct. The shRNA was designed to mimic human...
<p>(A) Genotyping of the SOD-1 (G93A)<sup>PS</sup> mouse reveals a characteristic band from the SOD-...
Prion diseases are progressive, neurodegenerative diseases affecting humans and animals. Also known ...
<p>The temporal mRNA expression profiles of M1 [CD86 (A), IL-1β (B), TNF-α (C) and NOX2 (D)] and M2 ...
<p>The log<sub>2</sub> transformation of the fold-change of the relative mRNA expression levels in t...
<p>A, expression of <i>Soat1</i> protein in transgenic mice. PC, positive control: lane loaded with ...
<p>Panel A and B. Quantification of <i>Sod1</i> mRNA expression in whole brain by real-time RT-PCR. ...
<p>(A) Semi-quantitative RT-PCR analysis confirmed that the identified mRNA species by DNA microarra...
Approximately 10 % of amyotrophic lateral sclerosis (ALS) cases are familial (FALS), and 25 % of FAL...
AbstractIn short hairpin RNA (shRNA) transgenic mice, the tissue difference in gene silencing effici...
<p>(A) Representative data for western blot analysis of the human mutant SOD1 proteins (hSOD1). The ...
<p>Total RNA extracted from brains of TgMHu2ME199K (tg), PrP <sup>0/0</sup> (ko) and wt mice, od des...
RNA interference (RNAi) has been used increasingly for reverse genetics in invertebrates and mammali...
<p>(A) Western blot analysis of GPx in the liver of the same control and HBV transgenic mice as desc...