Competition between Species during Co-Colonization of Immunocompetent Mice

<p>The density of <i>H. influenzae</i> strain <i>Hi</i>636 <i>(Hi)</i> and <i>S. pneumoniae</i> strain <i>Sp</i>1121 <i>(Sp)</i> in upper respiratory tract lavage was determined at 24 h after intranasal inoculation of C3H/HeOuJ mice. Box-and-whiskers plot indicates high and low values, median, and interquartile ranges; <i>n</i> ≥ 10 in each group. Co-inoculated species shown in parentheses. The lower limit of detection for bacteria in lavage culture was 10² CFU/ml.