<p>The upper sets of photomicrographs demonstrate examples of type I and type II cone gene derepression in the <i>rd7</i> mutant retina as explained in the main text. The bottom left images show several rod-specific genes that are essentially unchanged in the <i>rd7</i> background at P14. The bottom right images show the expression pattern of three photoreceptor transcription factors in the <i>rd7</i> mutant. Abbreviations in the lower left hand corner of each pair of panels represent the gene symbols summarized in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0010011#pgen-0010011-g001" target="_blank">Figure 1</a>.</p
NR2E3 is a photoreceptor-specific nuclear receptor, mutations in which have been identified in human...
Rod and cone photoreceptors are light-receptive cells in the visual system that convert photons into...
RPE65 is essential for both rod- and cone-mediated vision. So far, more than 120 disease-associated ...
Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectively. The...
<div><p>The color coding of text in the column “Gene Name” is as follows: light blue (G1–G15), genes...
Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectively. The...
<div><p>Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectiv...
<p><i>Gnb3</i> and <i>Thrb2</i> are both previously characterized cone genes that show staining at t...
<p>In the wild-type images (wt), note the scattered, weakly positive cells at the scleral edge of th...
<div><p>(A and B) Toluidine blue-stained semi-thin sections of the outer nuclear layer (scleral edge...
<p>Note the nearly undetectable staining for <i>rhodopsin</i> in this P6 mutant retina (top right). ...
The mammalian retina contains two types of photoreceptors, rods and cones, which mediate night visio...
There are two types of photosensitive cells of the retina that contribute to image formation: Cone p...
<p>Transcription factors that are selectively expressed in developing rods (and possibly cones as we...
The rd7 mouse is a model for hereditary retinal degeneration characterized clinically by retinal spo...
NR2E3 is a photoreceptor-specific nuclear receptor, mutations in which have been identified in human...
Rod and cone photoreceptors are light-receptive cells in the visual system that convert photons into...
RPE65 is essential for both rod- and cone-mediated vision. So far, more than 120 disease-associated ...
Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectively. The...
<div><p>The color coding of text in the column “Gene Name” is as follows: light blue (G1–G15), genes...
Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectively. The...
<div><p>Rod and cone photoreceptors subserve vision under dim and bright light conditions, respectiv...
<p><i>Gnb3</i> and <i>Thrb2</i> are both previously characterized cone genes that show staining at t...
<p>In the wild-type images (wt), note the scattered, weakly positive cells at the scleral edge of th...
<div><p>(A and B) Toluidine blue-stained semi-thin sections of the outer nuclear layer (scleral edge...
<p>Note the nearly undetectable staining for <i>rhodopsin</i> in this P6 mutant retina (top right). ...
The mammalian retina contains two types of photoreceptors, rods and cones, which mediate night visio...
There are two types of photosensitive cells of the retina that contribute to image formation: Cone p...
<p>Transcription factors that are selectively expressed in developing rods (and possibly cones as we...
The rd7 mouse is a model for hereditary retinal degeneration characterized clinically by retinal spo...
NR2E3 is a photoreceptor-specific nuclear receptor, mutations in which have been identified in human...
Rod and cone photoreceptors are light-receptive cells in the visual system that convert photons into...
RPE65 is essential for both rod- and cone-mediated vision. So far, more than 120 disease-associated ...