Organismal Life Span Is Independent of Telomere Length

<div><p>(A) Life span of N2 worms under control (green), <i>daf-2</i> (blue), and <i>daf-16</i> (red) RNAi suppression conditions. Worms were grown on bacteria expressing RNAi constructs targeting the indicated genes, and life span was assessed as described [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.0010030#pgen-0010030-b21" target="_blank">21</a>].</p><p>(B) Telomere length of nine individual control N2 clones was assessed as described. Samples were collected at the beginning (B) and end (E) of the experiment, and fragment size is indicated in kb.</p><p>(C) Telomere length of nine individual <i>daf-2</i> (RNAi) N2 clones was assessed as described in (B).</p><p>(D) Telomere length of nine individual <i>daf-16</i> (RNAi) N2 clones was assessed as described in (B).</p>