Analysis of Cell Surface Antigens of Thymomas from <i>Ews-ERG</i> Invertor Mice Using Flow Cytometry

<p>Thymus tissue was resected from mice with thymoma and FACS analysis performed to determine T cell phenotype (summarised in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0030242#pbio-0030242-t001" target="_blank">Table 1</a>). The data in the figure show representative flow diagrams of three tumour-bearing mice (M2, M3, and M4) compared with a wild-type C57BL/6 control (wt), using anti-Thy1 (<i>y</i>-axis) plus anti-B220 (<i>x-</i>axis) antibodies or using anti-CD8 (<i>y</i>-axis) plus anti-CD4 (<i>x</i>-axis) antibodies. The three thymomas show a range of CD4 and CD8 co-expression phenotypes characterizing the thymomas generated in the <i>Ews-ERG; Rag1-Cre</i> invertor mice..