The Distribution of VS Neurons Is Unaffected in Mice Over-Expressing SOX1 from the <i>Sox2</i>^R Allele

<div><p>(A–D), X-gal staining of coronal sections from the ventral telencephalon of P0 mice. Note that there is no difference in the distribution of <i>Sox2</i>-expressing OT neurons with SOX1 (A) or without SOX1 (C), and in <i>Sox2</i>^R/<i>+</i> mice with two wild-type <i>Sox1</i> alleles (A) or one (B). Comparison of the number and distribution of neurons expressing <i>Sox2</i>^βgeo in (C) and <i>Sox1</i>^βgeo in (D) shows overlapping expression. (A–C) show 150-μm sections, and (D) shows a 80-μm section.</p> <p>(E and F) DARPP-32 immunostaining of coronal sections from the ventral telencephalon of P10 <i>Sox2</i>^R/<i>+</i> and <i>Sox1</i>^βgeo/+ single heterozygous mice, showing no difference in the generation and migration of OT neurons. AC, anterior commissure. Scale bar = 100 μm.</p>