Expression of D-mib in Dorsal Cells Is Sufficient to Rescue the <i>D-mib</i> Mutant Phenotype

<div><p>(A) Expression of D-mib (green) in dorsal cells, using Ser-GAL4, rescued the growth of the wing pouch and margin Cut (red) expression in <i>D-mib²</i>/<i>D-mib³</i> mutant discs.</p> <p>(B–D′′′) Ser-GAL4-driven expression of YFP::D-mib (green) rescued the <i>D-mib²</i>/<i>D-mib³</i> phenotype and strongly reduced the level of Dl (blue in [B, B′, C, C′′, D, and D′′]) and Ser (red in [B, B′′, C, C′′′, D, and D′′′]) in dorsal cells. (C–D′′′) are high-magnification views (apical [C–C′′′] and basal [D–D′′′]) of the disc shown in (B–B′′). YFP::D-mib co-localized with Dl and Ser at the apical cortex in cells expressing only low levels of YFP::D-mib.</p> <p>Bar is 50 μm for (A–B′′) and 10 μm for (C–D′′′).</p>