<p>The AC initiates vulval development by secreting the LIN-3 growth factor independently of ROM-1. In response to the AC signal, the proximal VPCs up-regulate ROM-1 expression and start secreting LIN-3 in a ROM-1-dependent manner to relay the AC signal.</p
<div><p>LET-23 Epidermal Growth Factor Receptor (EGFR) signaling specifies the vulval cell fates dur...
AbstractHeterochronic genes control the timing of vulval development in the C. elegans hermaphrodite...
<p>The thickness of the inductive signal (IS) arrows indicates the relative levels received by the t...
and MAP kinase. Previous genetic analysis has suggested Ras/MAP kinase pathway do not affect the pat...
chor cell adopt vulval cell fates, whereas the three more distant VPCs adopt a default hypodermal fa...
The lin-3 gene is necessary for induction of the Caenorhabditis elegans vulva by the anchor cell. It...
<p>The fully formed vulva of <i>C. elegans</i> is generated post-embryonically from cell divisions o...
During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, act...
The development of the vulva of the nematode Caenorhabditis elegans is induced by a signal from the...
AbstractSpecification of vulval precursor cell (VPC) fates in C. elegans has served as an important ...
<p>(A) LET-23 EGFR is localized to both basal and apical membranes in the VPCs of wild-type animals....
<p>(A) Adult expression of <i>uIs45</i> in <i>syIs66[B0034.1::pes-10::GFP]</i> animals with vulF cel...
During Caenorhabditise legans vulval induction, multipotent precursors respond to an inductive signa...
SummaryActivation of EGFR-Ras-MAPK signaling in vulval precursor cells (VPCs) by LIN-3/EGF from the ...
AbstractFactors that determine the competence of cells to respond to extracellular cues are not well...
<div><p>LET-23 Epidermal Growth Factor Receptor (EGFR) signaling specifies the vulval cell fates dur...
AbstractHeterochronic genes control the timing of vulval development in the C. elegans hermaphrodite...
<p>The thickness of the inductive signal (IS) arrows indicates the relative levels received by the t...
and MAP kinase. Previous genetic analysis has suggested Ras/MAP kinase pathway do not affect the pat...
chor cell adopt vulval cell fates, whereas the three more distant VPCs adopt a default hypodermal fa...
The lin-3 gene is necessary for induction of the Caenorhabditis elegans vulva by the anchor cell. It...
<p>The fully formed vulva of <i>C. elegans</i> is generated post-embryonically from cell divisions o...
During C. elegans vulval development, the anchor cell (AC) in the somatic gonad expresses lin-3, act...
The development of the vulva of the nematode Caenorhabditis elegans is induced by a signal from the...
AbstractSpecification of vulval precursor cell (VPC) fates in C. elegans has served as an important ...
<p>(A) LET-23 EGFR is localized to both basal and apical membranes in the VPCs of wild-type animals....
<p>(A) Adult expression of <i>uIs45</i> in <i>syIs66[B0034.1::pes-10::GFP]</i> animals with vulF cel...
During Caenorhabditise legans vulval induction, multipotent precursors respond to an inductive signa...
SummaryActivation of EGFR-Ras-MAPK signaling in vulval precursor cells (VPCs) by LIN-3/EGF from the ...
AbstractFactors that determine the competence of cells to respond to extracellular cues are not well...
<div><p>LET-23 Epidermal Growth Factor Receptor (EGFR) signaling specifies the vulval cell fates dur...
AbstractHeterochronic genes control the timing of vulval development in the C. elegans hermaphrodite...
<p>The thickness of the inductive signal (IS) arrows indicates the relative levels received by the t...
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