Flanking Sequence Frequency Distributions for Six Representative Nucleotide–Cassette Combinations for (AC)₅ Microsatellites

<p>In each panel, the microsatellite is centrally placed, represented as a gap at position zero, and the cassette type, base, and number of sequences considered <i>(n)</i> are given. Frequency distributions are plotted with separate 95% confidence intervals for odd- and even-numbered positions (shading). Horizontal lines indicate mean frequencies for the 3′ and 5′ flanking regions, calculated separately. (A–F) illustrate the six main classes of patterning where either dinucleotide periodicity or 5′–3′ asymmetry are present, summarised for all cassette–base combinations in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.0020199#pbio-0020199-t001" target="_blank">Table 1</a>.