Mixed species biofilms inhibit epithelialization in porcine partial thickness wound model on day 2. A.
- Irena Pastar (381233)
- Aron G. Nusbaum (381234)
- Joel Gil (381235)
- Shailee B. Patel (381236)
- Juan Chen (61123)
- Jose Valdes (381237)
- Olivera Stojadinovic (381238)
- Lisa R. Plano (381239)
- Marjana Tomic-Canic (381240)
- Stephen C. Davis (381241)
Publication date
February 2013
DOIAbstract
<p>Simultaneous infection with USA300 and <i>P. aeruginosa</i> 09-010 (PA) significantly inhibited epithelialization (<b>*</b><i>p</i>≤0.05) when compared to wounds infected with single species or control (Ctrl) uninfected wounds (<b>**</b><i>p</i>≤0.001). USA300 delayed epithelialization when compared to uninfected wounds (Ctrl) (<b>**</b><i>p</i>≤0.001). <b>B.</b> Representative wounds stained with H&E are shown. White arrows indicate wound edges after initial wounding while black arrowheads point at the epithelialized edges of the migrating fronts. CR = crust.</p
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