<p>MECs were isolated from STK11<i><sup>−/−/</sup></i>NIC tumors and NIC mammary glands, followed by treatment with <b>a,</b> Rapamycin for 30 min. <b>b,</b> Torin 1 for 2 h and <b>c,</b> AZD8055 for 2 h, followed by western blot analysis for LDH, and PDH. Data are representative of three separate experiments, using three separate mice from each genotype.</p
<p>Expression levels of each marker are shown relative to the value found in tumors of <i>PyMT, Lcn2...
The activities of phosphohexose isomerase (EC. 5.3.1.9), isocitrate dehydrogenase (EC. 1.1.1.42) and...
<p>A549 tumor-bearing animals were injected with GLV-1h68, GLV-1h351 or GLV-1h408. Every week, serum...
<p>Mammary glands from WT mice and tumors from STK11<i><sup>−/−/</sup></i>NIC mice were excised and ...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
<p><b>A</b>. Targeted in vivo shRNA screen in NCH421k cells. From 11 glycolytic target genes, five s...
Alterations of serum lactic dehydrogenase (S-LDH) activity and isozyme during therapy in tumor-beari...
<div><p>Purpose</p><p>Glycine and serine are well-known, classic metabolites of glycolysis. Here, we...
<p>RNA was extracted from eight MMTV-induced mammary tumors; 5 from C3H mice (BF, BN, C, F, P) and 2...
<p>Plotted is the relative mRNA expression of glycosyltransferase enzymes in mouse liver in four mou...
<p>(A) Glucose metabolism pathway. Major metabolic enzymes and intermediates are shown. Genes identi...
<p>Seven mice in each group were examined. Data are mean±s.d. (n = 7 per group). Values in "" are hy...
<p>(<b>A</b>) Rapamycin blood levels (Rapa: ▪, Ve: □). Mice were bled before, and at days 1 and 7 po...
<p><i>A</i>, Quantitative RT-PCR analysis of the expression levels of gene markers associated with d...
<p>Expression levels of each marker are shown relative to the value found in tumors of <i>PyMT, Lcn2...
The activities of phosphohexose isomerase (EC. 5.3.1.9), isocitrate dehydrogenase (EC. 1.1.1.42) and...
<p>A549 tumor-bearing animals were injected with GLV-1h68, GLV-1h351 or GLV-1h408. Every week, serum...
<p>Mammary glands from WT mice and tumors from STK11<i><sup>−/−/</sup></i>NIC mice were excised and ...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
c-Myc (hereafter called Myc) belongs to a family of transcription factors that regulates cell growth...
<p><b>A</b>. Targeted in vivo shRNA screen in NCH421k cells. From 11 glycolytic target genes, five s...
Alterations of serum lactic dehydrogenase (S-LDH) activity and isozyme during therapy in tumor-beari...
<div><p>Purpose</p><p>Glycine and serine are well-known, classic metabolites of glycolysis. Here, we...
<p>RNA was extracted from eight MMTV-induced mammary tumors; 5 from C3H mice (BF, BN, C, F, P) and 2...
<p>Plotted is the relative mRNA expression of glycosyltransferase enzymes in mouse liver in four mou...
<p>(A) Glucose metabolism pathway. Major metabolic enzymes and intermediates are shown. Genes identi...
<p>Seven mice in each group were examined. Data are mean±s.d. (n = 7 per group). Values in "" are hy...
<p>(<b>A</b>) Rapamycin blood levels (Rapa: ▪, Ve: □). Mice were bled before, and at days 1 and 7 po...
<p><i>A</i>, Quantitative RT-PCR analysis of the expression levels of gene markers associated with d...
<p>Expression levels of each marker are shown relative to the value found in tumors of <i>PyMT, Lcn2...
The activities of phosphohexose isomerase (EC. 5.3.1.9), isocitrate dehydrogenase (EC. 1.1.1.42) and...
<p>A549 tumor-bearing animals were injected with GLV-1h68, GLV-1h351 or GLV-1h408. Every week, serum...