Metabolic response to antibiotic treatment.

a<p>Significant metabolites for <i>S. aureus</i> antibiotic treatment response common human <i>S. aureus</i> sepsis and mice infected with MRSA and MSSA, and human <i>S. aureus</i> sepsis and <i>in vitro</i> grown MRSA or MSSA.</p>b<p>Refers to response to antibiotic treatment, where ↑/↓ indicates a higher/lower metabolite concentration in samples with effective treatment compared to samples with ineffective treatment (for <i>in vitro</i> experiments and mice infection) and in late time point, 144 h-2 weeks after admittance, compared to acute phase infection samples, 0–24 h after admittance (for human sepsis).</p>c<p>Retention index for all metabolites.</p>d<p>Concentration obtained from direct quantification of the 7 metabolites in a subset of the <i>S. aureus</i> samples shown both for samples in the acute phase (0 h) and in the late phase (144 h).