<p>All the effects, including batch effects, profile effects, interaction between batch and profile effects, and residual effects, were estimated for their contribution to the overall variation by PVCA. (<b>A</b>) Data before batch adjustment. (<b>B</b>) Data processed by ComBat as batch adjustment tool/model. (<b>C</b>) Hierarchical clustering of the data before batch adjustment. (<b>D</b>) Hierarchical clustering of the data after batch adjustment.</p
Motivation: International consortia such as the Genotype-Tissue Expression (GTEx) project, The Cance...
Technical variation plays an important role in microarray-based gene expression studies, and batch e...
<p>We consider the PVCA plot of the HL clinical samples run in different batches after adjusting BE ...
The expression microarray is a frequently used approach to study gene expression on a genome-wide sc...
Batch effects refer to the systematic non-biological variability that is introduced by experimental ...
Microarray batch effect (BE) has been the primary bottleneck for large-scale integration of data fro...
<p>Overall gene expression was corrected for batch effects by either <i>ReplicateRUV</i> or <i>ComBa...
In the context of high-throughput molecular data analysis it is common that the observations include...
<p>Each color represents a batch of arrays, which were hybridized and processed at the same time. Ba...
<p>(A) The expression profile (denoted as variable E) in CMap is mainly determined by drug action (c...
<p>A simple batch effect dataset was simulated and visualized. This data has 5 dimensions, with 2 in...
Principal component analysis (PCA) of Homo sapiens (A–C) and Mus musculus (D–F). (A, D) and (B, E) d...
In microarray technology, many diverse experimental features can cause biases including RNA sources,...
<p>(A) Hierarchical clustering (performed using ArrayAssist) shows subsets of RAW264.7 macrophage ge...
International audienceTechnical variation plays an important role in microarray-based gene expressio...
Motivation: International consortia such as the Genotype-Tissue Expression (GTEx) project, The Cance...
Technical variation plays an important role in microarray-based gene expression studies, and batch e...
<p>We consider the PVCA plot of the HL clinical samples run in different batches after adjusting BE ...
The expression microarray is a frequently used approach to study gene expression on a genome-wide sc...
Batch effects refer to the systematic non-biological variability that is introduced by experimental ...
Microarray batch effect (BE) has been the primary bottleneck for large-scale integration of data fro...
<p>Overall gene expression was corrected for batch effects by either <i>ReplicateRUV</i> or <i>ComBa...
In the context of high-throughput molecular data analysis it is common that the observations include...
<p>Each color represents a batch of arrays, which were hybridized and processed at the same time. Ba...
<p>(A) The expression profile (denoted as variable E) in CMap is mainly determined by drug action (c...
<p>A simple batch effect dataset was simulated and visualized. This data has 5 dimensions, with 2 in...
Principal component analysis (PCA) of Homo sapiens (A–C) and Mus musculus (D–F). (A, D) and (B, E) d...
In microarray technology, many diverse experimental features can cause biases including RNA sources,...
<p>(A) Hierarchical clustering (performed using ArrayAssist) shows subsets of RAW264.7 macrophage ge...
International audienceTechnical variation plays an important role in microarray-based gene expressio...
Motivation: International consortia such as the Genotype-Tissue Expression (GTEx) project, The Cance...
Technical variation plays an important role in microarray-based gene expression studies, and batch e...
<p>We consider the PVCA plot of the HL clinical samples run in different batches after adjusting BE ...