<p><b><i>A</i></b>, Western blot and <b><i>B</i></b>, subsequent densitometry to show CASP2 and CASP3 protein levels after knockdown with relevant siRNA. <b><i>C</i></b>, and <b><i>D</i></b>, Immunocytochemistry to demonstrate CASP2 and CASP3 knockdown in DRGN and satellite cells by relevant siRNA, respectively. <b><i>E</i></b>, Quantification of DRGN and <b><i>F</i></b>, DRG glia survival after siRNA-mediated knockdown of CASP2 and CASP3. Scale bars in <i>C</i> and <i>D</i> = 50 µm.</p
Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspase...
<p>(A, B) NL20 and A549 cells treated with (lanes 2,4) and without (lanes 1,3) 1 µM STS for 3 hours ...
<p>As compared to vehicle-treated GFAP-GFP-labeled astrocytes (<b>A–C</b>), those treated with GC (<...
<p><b><i>A</i></b>, CASP2, C-CASP2 and <b><i>B</i></b>, CASP3, C-CASP3 in DRGN and satellite cells g...
<p><b><i>A</i></b>, <b><i>B</i></b>, Constitutive low levels of C-CASP2 and C-CASP3 in control DRGN ...
<p>Both NeuN –positive neurons and GFAP-positive glial cells undergo apoptosis in the dLGN. (A) Doub...
Sciatic nerve (SN) transection-induced apoptosis of dorsal root ganglion neurons (DRGN) is one facto...
<p>The patterns of C-CASP2 immunocytochemistry included cytosolic (arrow) but not nuclear expression...
<p>(A) Efficient Dsg2 (red) depletion was detected by immunofluorescence staining in HaCaT cells. Ac...
<p>Casp-2S was either over-expressed in A2780 and 2008 cells (A), or knocked down in CDDP cells and ...
<p>ER-dnE2F1 cells were transfected with siRNA specific for PTP-1B (+PTP-1B), SHP-2 (+SHP-2), or PTE...
<p>(A, B) Western blot analysis of cleaved caspase 3 (CASP3) expression and caspase 3 activity in co...
<p>C-CASP3 localisation in DRGN grown in both the presence of serum (D+S) and after serum withdrawal...
<p><b>a.</b> VCaP cells were transfected with siRNA (TMPRSS2-ERG III, IV or siRNA Control) at 50 nM ...
Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspase...
Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspase...
<p>(A, B) NL20 and A549 cells treated with (lanes 2,4) and without (lanes 1,3) 1 µM STS for 3 hours ...
<p>As compared to vehicle-treated GFAP-GFP-labeled astrocytes (<b>A–C</b>), those treated with GC (<...
<p><b><i>A</i></b>, CASP2, C-CASP2 and <b><i>B</i></b>, CASP3, C-CASP3 in DRGN and satellite cells g...
<p><b><i>A</i></b>, <b><i>B</i></b>, Constitutive low levels of C-CASP2 and C-CASP3 in control DRGN ...
<p>Both NeuN –positive neurons and GFAP-positive glial cells undergo apoptosis in the dLGN. (A) Doub...
Sciatic nerve (SN) transection-induced apoptosis of dorsal root ganglion neurons (DRGN) is one facto...
<p>The patterns of C-CASP2 immunocytochemistry included cytosolic (arrow) but not nuclear expression...
<p>(A) Efficient Dsg2 (red) depletion was detected by immunofluorescence staining in HaCaT cells. Ac...
<p>Casp-2S was either over-expressed in A2780 and 2008 cells (A), or knocked down in CDDP cells and ...
<p>ER-dnE2F1 cells were transfected with siRNA specific for PTP-1B (+PTP-1B), SHP-2 (+SHP-2), or PTE...
<p>(A, B) Western blot analysis of cleaved caspase 3 (CASP3) expression and caspase 3 activity in co...
<p>C-CASP3 localisation in DRGN grown in both the presence of serum (D+S) and after serum withdrawal...
<p><b>a.</b> VCaP cells were transfected with siRNA (TMPRSS2-ERG III, IV or siRNA Control) at 50 nM ...
Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspase...
Caspase-2 (casp-2) is the most conserved caspase across species, and is one of the initiator caspase...
<p>(A, B) NL20 and A549 cells treated with (lanes 2,4) and without (lanes 1,3) 1 µM STS for 3 hours ...
<p>As compared to vehicle-treated GFAP-GFP-labeled astrocytes (<b>A–C</b>), those treated with GC (<...