Hemagglutination inhibition titers detected in sera of rabbits immunized with the recombinant VLP and challenged with RHDV.

a<p>The HI titer was expressed as the maximum dilution capable to completely inhibit the agglutination of human type O erythrocytes by RHDV. Each titer value corresponds to an individual animal. In the assay, a hyperimmune serum against RHDV (with an HI titer of 1/2048) was used as positive control. All animals were immunized at days 0 and 21. n.d.: hemagglutination inhibition titers not detected.</p>b<p>The result is also expressed as the mean ± standard deviation of inhibition values obtained in cELISA from individual animals. Different letters within a row indicate statistical significant differences for <i>p</i><0.05, according to the Kruskal-Wallis and Dunn’s tests.