Cardiovascular function in anesthetized 7-month-old mice that were postnatally overfed (OF) by litter size reduction (3 pups/litter) or normally fed (NF) in litters of normal size (10 pups/litter).

<p>A: Diastolic (DBP), systolic (SBP) and mean arterial blood pressure (MABP) measured at 7 months by plethysmography. B: Evolution of left ventricular ejection fraction (LVEF, in %) from 3 months to 7 months of life, measured in vivo by echocardiography. C: Evolution of left ventricular internal diameter (LVID) from 3 months to 7 months of life, measured in vivo by echocardiography. *, P<0.05; ***, P<0.001 were considered significantly different from NF mice. D: left ventricular ejection fraction measured at 7 months in anesthetized NF and OF mice by echocardiography (LVEF, in %). E: left ventricular end diastolic diameter (LVEDD) and left ventricular end systolic diameter (LVESD) measured at 7 months in anesthetized NF and OF mice by echocardiography. Data are expressed as means ± SEM from 10 animals per group. P was calculated by Student’s <i>t</i>-test.