Effects of nab-paclitaxel therapy on the overall survival of mice.

<p>(A) Antitumor effect of nab-paclitaxel compared with oxaliplatin. SNU cells (40×10⁶) were injected intraperitoneally into SCID mice, followed by treatment after 2 weeks with nab-paclitaxel (10 mg/kg, 2 times a week) and oxaliplatin (5 mg/kg, 2 times a week) for 2 weeks. (B) Antitumor effect of nab-paclitaxel compared with oxaliplatin and docetaxel. SNU cells (40×10⁶) were injected intraperitoneally into SCID mice, followed by treatment after 2 weeks with nab-paclitaxel (10 mg/kg, 2 times a week), oxaliplatin (5 mg/kg, 2 times a week), or docetaxel (3 mg/kg, 2 times a week) for 2 weeks. The curve represents the animal survival time from the beginning of therapy. Symbol * represents significant difference compared with vehicle control (p<0.05), symbol ^§ represents significant differences compared with oxaliplatin (p<0.05), and symbol ^# represents significant differences compared with docetaxel (p<0.05).