A Novel Triphosphoramidite Ligand for Highly Regioselective Linear Hydroformylation of Terminal and Internal Olefins

The first triphosphorus ligand has been designed and synthesized for highly regioselective linear hydroformylations. A very high <i><i>l</i></i>/<i><i>b</i></i> ratio (up to 471, 99.8% linear selectivity) was obtained in the linear hydroformylation of representative terminal and internal olefins. For the range of substrates tested, the regioselectivities achieved utilizing the novel triphosphoramidite ligand were much better than those of the bisphosphoramidite ligand and close to those of the tetraphosphoramidite ligand