Baseline quantitative sensory testing measurements for the pregabalin treated group (n = 31).

Population pharmacokinetic/pharmacodynamic analysis of nociceptive pain models following an oral pregabalin dose administration to healthy subjects

van Esdonk, Michiel J
Lindeman, Ian
Okkerse, Pieter
de Kam, Marieke L
Groeneveld, Geert J
Stevens, Jasper

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial

Stefan A. W. Bouwense
Søren S. Olesen
Asbjørn M. Drewes
Jan-werner Poley
Harry Van Goor
Oliver H. G. Wilder-smith

August 2016

Background: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial.

Bouwense, S.A.W.
Olesen, S.S.
Drewes, A.M.
Poley, J.W.
Goor, H. van
Wilder-Smith, O.H.G.

January 2012

BACKGROUND: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Conditioned pain modulation and pain thresholds for pregabalin vs. placebo before and after study treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Electrical pain detection tolerance (ePDT) ratios for responders and non-responders in the pregabalin group.

Søren S. Olesen (144777)
Carina Graversen (384680)
Stefan A. W. Bouwense (144775)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)
Asbjørn M. Drewes (144781)

March 2013

The optimal ratio to separate responder from non-responders was 1.41 (dotted line). This threshol...

Change and percentage change in conditioned pain modulation and pain thresholds for pregabalin vs. placebo after study treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Predictive power of baseline QST measurements.

Søren S. Olesen (144777)
Carina Graversen (384680)
Stefan A. W. Bouwense (144775)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)
Asbjørn M. Drewes (144781)

March 2013

The SVM was used to screen baseline QST measurements for their predictive power of analgesic resp...

Sum of pain thresholds for pregabalin vs. placebo before and after treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Quantitative Sensory Testing Predicts Pregabalin Efficacy in Painful Chronic Pancreatitis

Olesen Søren S.
Graversen Carina
Bouwense Stefan A. W.
van Goor Harry
Wilder-Smith Oliver H. G.
Drewes Asbjørn M.

March 2013

A major problem in pain medicine is the lack of knowledge about which treatment suits a specific pat...

Quantitative sensory testing predicts pregabalin efficacy in painful chronic pancreatitis

Olesen, S.S.
Graversen, C.
Bouwense, S.A.W.
Goor, H. van
Wilder-Smith, O.H.G.
Drewes, A.M.

January 2013

BACKGROUND: A major problem in pain medicine is the lack of knowledge about which treatment suits a ...

Quantitative sensory testing predicts pregabalin efficacy in painful chronic pancreatitis.

Søren S Olesen
Carina Graversen
Stefan A W Bouwense
Harry van Goor
Oliver H G Wilder-Smith
Asbjørn M Drewes

BACKGROUND: A major problem in pain medicine is the lack of knowledge about which treatment suits a ...

Effect of imipramine on quantitative sensory tests.

Jürg Schliessbach (5194409)
Andreas Siegenthaler (5194418)
Lukas Bütikofer (4101319)
Andreas Limacher (591356)
Peter Juni (5194415)
Pascal H. Vuilleumier (390482)
Ulrike Stamer (5194412)
Lars Arendt-Nielsen (390485)
Michele Curatolo (390486)

May 2018

Imipramine effect on pressure pain detection (PPDT, a) and tolerance thresholds (PPTT, b), and on...

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

Michiel J. vanEsdonk
Ian Lindeman
Pieter Okkerse
Marieke L. deKam
Geert J. Groeneveld
Jasper Stevens

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Differences in quantitative sensory assessments on the pain side from baseline to 1 month after patch application.

Joakim M. Bischoff (641038)
Thomas K. Ringsted (417489)
Marian Petersen (641039)
Claudia Sommer (230646)
Nurcan Üçeyler (226246)
Mads U. Werner (411781)

October 2014

Values are mean (95% CI)§ or median (95% CI). Δ value = post-treatment minus baseline ...

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

Esdonk, M.J. van
Lindeman, I.
Okkerse, P.
Kam, M.L. de
Groeneveld, G.J.
Stevens, J.

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Population pharmacokinetic/pharmacodynamic analysis of nociceptive pain models following an oral pregabalin dose administration to healthy subjects

van Esdonk, Michiel J
Lindeman, Ian
Okkerse, Pieter
de Kam, Marieke L
Groeneveld, Geert J
Stevens, Jasper

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial

Stefan A. W. Bouwense
Søren S. Olesen
Asbjørn M. Drewes
Jan-werner Poley
Harry Van Goor
Oliver H. G. Wilder-smith

August 2016

Background: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial.

Bouwense, S.A.W.
Olesen, S.S.
Drewes, A.M.
Poley, J.W.
Goor, H. van
Wilder-Smith, O.H.G.

January 2012

BACKGROUND: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Conditioned pain modulation and pain thresholds for pregabalin vs. placebo before and after study treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Electrical pain detection tolerance (ePDT) ratios for responders and non-responders in the pregabalin group.

Søren S. Olesen (144777)
Carina Graversen (384680)
Stefan A. W. Bouwense (144775)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)
Asbjørn M. Drewes (144781)

March 2013

The optimal ratio to separate responder from non-responders was 1.41 (dotted line). This threshol...

Change and percentage change in conditioned pain modulation and pain thresholds for pregabalin vs. placebo after study treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Predictive power of baseline QST measurements.

Søren S. Olesen (144777)
Carina Graversen (384680)
Stefan A. W. Bouwense (144775)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)
Asbjørn M. Drewes (144781)

March 2013

The SVM was used to screen baseline QST measurements for their predictive power of analgesic resp...

Sum of pain thresholds for pregabalin vs. placebo before and after treatment.

Stefan A. W. Bouwense (144775)
Søren S. Olesen (144777)
Asbjørn M. Drewes (144781)
Jan-Werner Poley (144785)
Harry van Goor (18163)
Oliver H. G. Wilder-Smith (144794)

August 2012

All values are medians with interquartile ranges. • = Measurements after study treatment were s...

Quantitative Sensory Testing Predicts Pregabalin Efficacy in Painful Chronic Pancreatitis

Olesen Søren S.
Graversen Carina
Bouwense Stefan A. W.
van Goor Harry
Wilder-Smith Oliver H. G.
Drewes Asbjørn M.

March 2013

A major problem in pain medicine is the lack of knowledge about which treatment suits a specific pat...

Quantitative sensory testing predicts pregabalin efficacy in painful chronic pancreatitis

Olesen, S.S.
Graversen, C.
Bouwense, S.A.W.
Goor, H. van
Wilder-Smith, O.H.G.
Drewes, A.M.

January 2013

BACKGROUND: A major problem in pain medicine is the lack of knowledge about which treatment suits a ...

Quantitative sensory testing predicts pregabalin efficacy in painful chronic pancreatitis.

Søren S Olesen
Carina Graversen
Stefan A W Bouwense
Harry van Goor
Oliver H G Wilder-Smith
Asbjørn M Drewes

BACKGROUND: A major problem in pain medicine is the lack of knowledge about which treatment suits a ...

Effect of imipramine on quantitative sensory tests.

Jürg Schliessbach (5194409)
Andreas Siegenthaler (5194418)
Lukas Bütikofer (4101319)
Andreas Limacher (591356)
Peter Juni (5194415)
Pascal H. Vuilleumier (390482)
Ulrike Stamer (5194412)
Lars Arendt-Nielsen (390485)
Michele Curatolo (390486)

May 2018

Imipramine effect on pressure pain detection (PPDT, a) and tolerance thresholds (PPTT, b), and on...

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

Michiel J. vanEsdonk
Ian Lindeman
Pieter Okkerse
Marieke L. deKam
Geert J. Groeneveld
Jasper Stevens

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Differences in quantitative sensory assessments on the pain side from baseline to 1 month after patch application.

Joakim M. Bischoff (641038)
Thomas K. Ringsted (417489)
Marian Petersen (641039)
Claudia Sommer (230646)
Nurcan Üçeyler (226246)
Mads U. Werner (411781)

October 2014

Values are mean (95% CI)§ or median (95% CI). Δ value = post-treatment minus baseline ...

Population Pharmacokinetic/Pharmacodynamic Analysis of Nociceptive Pain Models Following an Oral Pregabalin Dose Administration to Healthy Subjects

Esdonk, M.J. van
Lindeman, I.
Okkerse, P.
Kam, M.L. de
Groeneveld, G.J.
Stevens, J.

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Population pharmacokinetic/pharmacodynamic analysis of nociceptive pain models following an oral pregabalin dose administration to healthy subjects

van Esdonk, Michiel J
Lindeman, Ian
Okkerse, Pieter
de Kam, Marieke L
Groeneveld, Geert J
Stevens, Jasper

September 2018

A battery of pain models can be used in clinical trials to investigate the efficacy and to establish...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial

Stefan A. W. Bouwense
Søren S. Olesen
Asbjørn M. Drewes
Jan-werner Poley
Harry Van Goor
Oliver H. G. Wilder-smith

August 2016

Background: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Effects of pregabalin on central sensitization in patients with chronic pancreatitis in a randomized, controlled trial.

Bouwense, S.A.W.
Olesen, S.S.
Drewes, A.M.
Poley, J.W.
Goor, H. van
Wilder-Smith, O.H.G.

January 2012

BACKGROUND: Intense abdominal pain is the dominant feature of chronic pancreatitis. During the disea...

Baseline quantitative sensory testing measurements for the pregabalin treated group (n = 31).

Abstract

Extracted data

Baseline quantitative sensory testing measurements for the pregabalin treated group (n = 31).

Abstract

Extracted data

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