<p>The baseline was drawn at a value of 1 (average for the sham group) (**<i>p</i><0.01; *<i>p</i><0.05; ‡<i>p</i><0.01; †<i>p</i><0.05, compared to sham group). <b>A)</b> Expressions of TNF-α mRNA at the crushed nerve. <b>B)</b> Expression of IL-6 mRNA at the crushed nerve. <b>C)</b> Expression of MCP-1 mRNA at the crushed nerve. <b>D)</b> Expression of IL-1 mRNA at the crushed nerve. <b>E)</b> Expression of P2RX7 mRNA at the crushed nerve. <b>F)</b> Expression of Nav1.3 mRNA at the L5 DRG. <b>G)</b> Expression of Nav1.8 mRNA at the L5 DRG. <b>H)</b> Expression of Nav1.9 mRNA at the L5 DRG.</p
Background: Peripheral cytokines affect central nervous system (CNS) function, triggering anxiety an...
<p><b>A.</b> Sketch of the sciatic nerve with the chronic constriction injury sutures in place. <b>B...
Etanercept is a tumor necrosis factor antagonist with anti-inflammatory effects. The aim of our stud...
<p>Protein levels of TNF-α (<b>A</b>) and IL-6 (<b>B</b>) were determined in homogenized sciatic ner...
<p>Variations in sciatic functional index between groups after nerve crush injury. Sciatic functiona...
Tumor necrosis factor-a plays important roles in immune system development, immune response regulati...
<p>Values are fold expression relative to naïve animals, shown as mean ± SEM (<i>n</i> = 6). Signifi...
<p>ATF3 (<b>A</b>), NPY (<b>B</b>), IL-6 (<b>C</b>) and CGRP (<b>D</b>) mRNA expression were measure...
<p>RNA was extracted from 4(placebo). Systemic simvastatin suppresses the increase significantly (n ...
<p>Panel A: Gal mRNA levels in DRG after sciatic nerve-pinch injury at day 8, 16, and 24 without or ...
<p>Data were expressed as mean ± SD (n = 10 in each group). *<i>P</i><0.05 versus the sham group, <s...
<p><b>(A)</b> Histogram compared the expression of miR-sc8 in proximal nerve at indicated different ...
<p>Cells were treated with 10, 50, ng/mL of TNFα or H<sub>2</sub>O vehicle for 6 h. RNA was isolated...
Objective: To establish whether etanercept, a TNF-alpha antagonist, is an alternative and effective ...
To observe the effect of delayed administration of etanercept on the motor function, the expression ...
Background: Peripheral cytokines affect central nervous system (CNS) function, triggering anxiety an...
<p><b>A.</b> Sketch of the sciatic nerve with the chronic constriction injury sutures in place. <b>B...
Etanercept is a tumor necrosis factor antagonist with anti-inflammatory effects. The aim of our stud...
<p>Protein levels of TNF-α (<b>A</b>) and IL-6 (<b>B</b>) were determined in homogenized sciatic ner...
<p>Variations in sciatic functional index between groups after nerve crush injury. Sciatic functiona...
Tumor necrosis factor-a plays important roles in immune system development, immune response regulati...
<p>Values are fold expression relative to naïve animals, shown as mean ± SEM (<i>n</i> = 6). Signifi...
<p>ATF3 (<b>A</b>), NPY (<b>B</b>), IL-6 (<b>C</b>) and CGRP (<b>D</b>) mRNA expression were measure...
<p>RNA was extracted from 4(placebo). Systemic simvastatin suppresses the increase significantly (n ...
<p>Panel A: Gal mRNA levels in DRG after sciatic nerve-pinch injury at day 8, 16, and 24 without or ...
<p>Data were expressed as mean ± SD (n = 10 in each group). *<i>P</i><0.05 versus the sham group, <s...
<p><b>(A)</b> Histogram compared the expression of miR-sc8 in proximal nerve at indicated different ...
<p>Cells were treated with 10, 50, ng/mL of TNFα or H<sub>2</sub>O vehicle for 6 h. RNA was isolated...
Objective: To establish whether etanercept, a TNF-alpha antagonist, is an alternative and effective ...
To observe the effect of delayed administration of etanercept on the motor function, the expression ...
Background: Peripheral cytokines affect central nervous system (CNS) function, triggering anxiety an...
<p><b>A.</b> Sketch of the sciatic nerve with the chronic constriction injury sutures in place. <b>B...
Etanercept is a tumor necrosis factor antagonist with anti-inflammatory effects. The aim of our stud...