<p>All metabolites were evaluated by HPLC as described under <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1003180#s4" target="_blank">Methods</a>. ATP, ADP, AMP, AN (ATP+ADP+AMP), NAD, NADH and NAD+NADH were calculated as nmol/midgut and data are represented as fold of NTG values. The NTG values were the average of 3 d and 18 d given that no statistical differences were observed between these two days. Data were analyzed relative to NTG values with Student's t-test (alpha = 0.05).*<i>P</i><0.05 relative to NTG values.</p
<p>Posterior midgut morphology of NTG <i>An. stephensi</i> (3 d (A) and 18 d (B) after adult emergen...
<p>Identical superscripts indicate values significant differences with the following <i>P</i> values...
<p>Expression profiles of <b>(A)</b> <i>MESH</i> and <b>(B)</b> <i>DUOX1</i> in the mosquito midgut ...
<p>The number and size of mitochondria in the posterior midgut of myrAkt TG and NTG mosquitoes were ...
<p>Significant changes were observed in the metabolic profile of the midgut upon infection. (A) The ...
<p>(A and B) Relative levels for intermediary metabolites of glycolysis (A) and the citrate cycle (B...
<p>(A) A decrease in the glycogen levels was observed in Met-depleted adult female mosquitoes, as me...
<p>Summary of metabolites from mosquito midguts detected across all time points and treatments.</p
<p>(A) 3–5 d old, age-matched non-blood-fed NTG (nbf NTG), (B) blood-fed (bf) NTG and (C) HM female ...
<p>(A) Endogenous levels of glycogen during PE (<i>top panel</i>) and PBM (<i>bottom panel</i>) phas...
<p>Top panel, representative western blots probed for nitrotyrosine (nY) and total ATPase beta subun...
The mosquito midgut is a physiological organ essential for the nutrient acquisition as well as an in...
Non-transgenic (control) A. stephensi (3–5 day old) were fed on artificial blood meals containing 2....
<p>Peroxide levels in midguts at 72(A) and one week (D) following IGF1 treatment. Peroxides were qua...
<p>Whole midguts from 150 NTG and 150 HM <i>An. stephensi</i> at 3-d post-adult emergence were each ...
<p>Posterior midgut morphology of NTG <i>An. stephensi</i> (3 d (A) and 18 d (B) after adult emergen...
<p>Identical superscripts indicate values significant differences with the following <i>P</i> values...
<p>Expression profiles of <b>(A)</b> <i>MESH</i> and <b>(B)</b> <i>DUOX1</i> in the mosquito midgut ...
<p>The number and size of mitochondria in the posterior midgut of myrAkt TG and NTG mosquitoes were ...
<p>Significant changes were observed in the metabolic profile of the midgut upon infection. (A) The ...
<p>(A and B) Relative levels for intermediary metabolites of glycolysis (A) and the citrate cycle (B...
<p>(A) A decrease in the glycogen levels was observed in Met-depleted adult female mosquitoes, as me...
<p>Summary of metabolites from mosquito midguts detected across all time points and treatments.</p
<p>(A) 3–5 d old, age-matched non-blood-fed NTG (nbf NTG), (B) blood-fed (bf) NTG and (C) HM female ...
<p>(A) Endogenous levels of glycogen during PE (<i>top panel</i>) and PBM (<i>bottom panel</i>) phas...
<p>Top panel, representative western blots probed for nitrotyrosine (nY) and total ATPase beta subun...
The mosquito midgut is a physiological organ essential for the nutrient acquisition as well as an in...
Non-transgenic (control) A. stephensi (3–5 day old) were fed on artificial blood meals containing 2....
<p>Peroxide levels in midguts at 72(A) and one week (D) following IGF1 treatment. Peroxides were qua...
<p>Whole midguts from 150 NTG and 150 HM <i>An. stephensi</i> at 3-d post-adult emergence were each ...
<p>Posterior midgut morphology of NTG <i>An. stephensi</i> (3 d (A) and 18 d (B) after adult emergen...
<p>Identical superscripts indicate values significant differences with the following <i>P</i> values...
<p>Expression profiles of <b>(A)</b> <i>MESH</i> and <b>(B)</b> <i>DUOX1</i> in the mosquito midgut ...