The affect of DNA strand and mutations in the G–motif on quadruplex formation.

<p><b>A,C)</b> Oligonucleotides corresponding to the wild-type 14-mer and 17-mer top (see <b>Fig. 4</b>) and bottom strands, and mutated top strands in which four successive G’s were substituted with TATA. <b>B,D)</b> Autoradiogram of a 20% native gel run to assess G4 formation, as described in <b>Fig. 4</b>.