<p>(A) <i>H. pylori</i> was isolated from C57BL/6 WT or RAG1−/− mice (N = 3–6/time point) 8 weeks after experimental infection with <i>H. pylori</i> PMSS1. Individual colonies (3–6/mouse) were co-cultured with AGS cells, and ELISA was used to measure IL-8 levels, which were normalized to the PMSS1 positive control (line = mean). Each data point represents the results from a single colony. Induction of IL-8 in colonies isolated from WT mice was significantly lower than in RAG1−/− mice, and was associated with changes in <i>cagY</i> PCR-RFLP (open circles). (B) <i>cagY</i> in <i>H. pylori</i> strain SS1 is larger than that in the progenitor strain PMSS1, and has a different fingerprint on PCR-RFLP. (C) Deletion of <i>cagY</i> from WT <i>H. py...
<p>B6129 WT and Cav1-KO mice (n = 15 per group) were infected with the mouse-adapted CagA-delivery i...
<p>(A) Reduced expression of mouse C<i>av1</i> mRNA after an 11-month infection with CagA-delivery d...
<p>(A) Warthin starry staining revealed a stable colonization of the SS1 strain over 50 wpi, whereas...
<p><i>H. pylori</i> was isolated from C57BL/6 WT (A) or RAG2−/− (B) mice (N = 3–6/time point) up to ...
<p>Deletion of <i>cagY</i> (▵Y) from WT <i>H. pylori</i> J166 significantly reduced its capacity to ...
<p>(A) Co-culture of <i>H. pylori</i> with AGS cells stably transformed with a reporter plasmid demo...
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV sec...
<p>(A–E) <i>H. pylori</i> was isolated from five rhesus macaques up to 14 months after experimental ...
<p>(A) C57BL/6 mice were challenged with Brucella broth, as an uninfected (UI) negative control, wit...
<p>WT and B7-H1<sup>-/-</sup> C57BL/6 mice were challenged with <i>H</i>. <i>pylori</i> strain PMSS1...
Chronic Helicobacter pylori colonization in animal models often leads to downregulation of the type ...
<p>Deletion of <i>cagY</i> (▵Y) from WT <i>H. pylori</i> J166 significantly reduced its capacity to ...
<p><b>A)</b> qRT-PCR detection of TIFA transcript in AGS wt and AGS TIFA k/o (KO) cells. Cells were ...
Background & aimsPeptic ulcer disease and gastric cancer are caused most often by Helicobacter p...
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV sec...
<p>B6129 WT and Cav1-KO mice (n = 15 per group) were infected with the mouse-adapted CagA-delivery i...
<p>(A) Reduced expression of mouse C<i>av1</i> mRNA after an 11-month infection with CagA-delivery d...
<p>(A) Warthin starry staining revealed a stable colonization of the SS1 strain over 50 wpi, whereas...
<p><i>H. pylori</i> was isolated from C57BL/6 WT (A) or RAG2−/− (B) mice (N = 3–6/time point) up to ...
<p>Deletion of <i>cagY</i> (▵Y) from WT <i>H. pylori</i> J166 significantly reduced its capacity to ...
<p>(A) Co-culture of <i>H. pylori</i> with AGS cells stably transformed with a reporter plasmid demo...
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV sec...
<p>(A–E) <i>H. pylori</i> was isolated from five rhesus macaques up to 14 months after experimental ...
<p>(A) C57BL/6 mice were challenged with Brucella broth, as an uninfected (UI) negative control, wit...
<p>WT and B7-H1<sup>-/-</sup> C57BL/6 mice were challenged with <i>H</i>. <i>pylori</i> strain PMSS1...
Chronic Helicobacter pylori colonization in animal models often leads to downregulation of the type ...
<p>Deletion of <i>cagY</i> (▵Y) from WT <i>H. pylori</i> J166 significantly reduced its capacity to ...
<p><b>A)</b> qRT-PCR detection of TIFA transcript in AGS wt and AGS TIFA k/o (KO) cells. Cells were ...
Background & aimsPeptic ulcer disease and gastric cancer are caused most often by Helicobacter p...
Helicobacter pylori is the major risk factor for gastric cancer. H. pylori harboring the type IV sec...
<p>B6129 WT and Cav1-KO mice (n = 15 per group) were infected with the mouse-adapted CagA-delivery i...
<p>(A) Reduced expression of mouse C<i>av1</i> mRNA after an 11-month infection with CagA-delivery d...
<p>(A) Warthin starry staining revealed a stable colonization of the SS1 strain over 50 wpi, whereas...