Sequencing and mapping messages of hepatic mRNA profiling of normal and diabetic mice.

<p>(A) The high-quality clean reads from high-throughput sequencing. Total liver RNA from 9-week-old normal (N) and diabetic (DB) db/db mice was used to prepare the high-throughput sequencing library. (B) The proportions of high-quality clean reads unmapped and/or mapped to unique genes, multiple genes and genome. (C) The number of genes detected in normal and diabetic mouse liver. (D) The top 15 abundance change genes downregulated or upregulated in diabetic mouse liver. (E) The top 15 fold change genes downregulated or upregulated in diabetic mouse liver.