Blockade of IL-17 alleviated the severity of lupus nephritis.

<p>Groups of BALB/c mice were injected with neutralizing antibody to IL-17 or the control antibody, and then immunized with 50 µg of ALD-DNA. (A and B) The kidney histopathology and pathology score were analyzed eight weeks post ALD-DNA injection. (C) The level of urine protein was analyzed at the indicated time. Data represented the means (±SD) for eight mice in each group. *P<0.05.