CoupTFI Is Required For The RA Mediated Rescue Of Foxc1-Mutants Animals.

<p>Quantification of dorsal forebrain length at E14.5 (A), Pax6 cell number at E14.5 (B), Tbr2 cell number at E14.5 (C), Ctip2 cell number at E14.5 (D), Tbr1 cell number at E14.5 (E), area of the counting window (F), density of DAPI⁺ cells in the counting window (G). Error bars represent SEM. A–G were analyzed by two way ANOVA: A: genotype (F_(3,25) = 55.86, p<0.001), treatment (F_(1,25) = 27.84, p<0.001), interaction (F_(3,25) = 49.98, p<0.001); B: genotype (F_(3,26) = 9.5, p<0.001), treatment (F_(1,26) = 48.66, p<0.01), interaction (F_(3,26) = 11.67, p<0.001); C: genotype (F_(3,27) = 19.23, p<0.001), treatment (F_(1,27) = 8.71, p<0.01), interaction (F_(3,27) = 14.55, p<0.001); D: genotype (F_(3,26) = 40.83, p<0.001), treatment (F_(1,26) = 18.45, p<0.001), interaction (F_(3,26) = 14.75, p<0.001); E: genotype (F_(3,26) = 47.99, p<0.001), treatment (F_(1,26) = 48.66, p<0.001), interaction (F_(3,26) = 14.91, p<0.001); F: genotype (F_(3,24) = 24.77, p<0.001), treatment (F_(1,24) = 8.158, p<0.01), interaction (F_(3,24) = 13.38, p<0.001); G: genotype (F_{(3,25) =}10.33, p<0.001), treatment (F_{(1,25) =}0.53, p = 0.47), interaction (F_(3,25) = 1.62, p = 0.2). *p<0.05, ***p<0.001 and indicate significance for Bonferroni’s Multiple Comparison Test posthoc analysis. Asterisks directly above the bar indicate significance from untreated control; within group differences are indicated by connected lines.