<p>Quantitated targetted molecular species of phosphoinositides PtdIns, PtdInsP and PtdInsP<sub>2</sub> in LPIAT1<sup>+/+</sup> (WT) or LPIAT1<sup>−/−</sup> (KO) brain samples presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058425#pone-0058425-g006" target="_blank">Figure 6</a>, and phospholipids PA,PC,PE and PS from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0058425#pone-0058425-g005" target="_blank">Figure 5</a> were added to calculate total levels for each lipid. Data are mean ± SD, n = 4 for both WT and KO. *p≤0.05, **p≤0.005, T-test.</p
Niemann-Pick type C (NP-C) disease is a neurodegenerative disease with a typically paediatric onset,...
Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is conti...
Phospholipase D2 (PLD2) is an enzyme that produces phosphatidic acid (PA), a lipid messenger molecul...
<p>Brains from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
<p>Brains from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
<p>Brains (<b>A</b>) or livers (<b>B</b>) from 13 day old littermates expressing (LPIAT1<sup>+/+</su...
<p>Livers from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
We disrupted the gene encoding lysophosphatidylinositol-acyltransferase-1 (LPIAT1) in the mouse with...
<div><p>We disrupted the gene encoding lysophosphatidylinositol-acyltransferase-1 (LPIAT1) in the mo...
<p>Targeted lipidomic analysis of NSC<sup>WT</sup> and NSC<sup>KO</sup> cells treated with or withou...
<p><b>A-F</b> Lipidomic analysis of six regions of the brain indicate that PLD2KO mice have signific...
Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a key ...
Objective: Non-alcoholic fatty liver disease (NAFLD) is a common prelude to cirrhosis and hepatocell...
Pre-treatment with polyunsaturated fatty acids or bioactive lipid mediators has been shown to reduce...
Lysophosphatidic acid (LPA) is not only a simple phos-pholipid constituent of cell membranes but als...
Niemann-Pick type C (NP-C) disease is a neurodegenerative disease with a typically paediatric onset,...
Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is conti...
Phospholipase D2 (PLD2) is an enzyme that produces phosphatidic acid (PA), a lipid messenger molecul...
<p>Brains from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
<p>Brains from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
<p>Brains (<b>A</b>) or livers (<b>B</b>) from 13 day old littermates expressing (LPIAT1<sup>+/+</su...
<p>Livers from 13 day old littermates expressing (LPIAT1<sup>+/+</sup> (WT)) or lacking (LPIAT1<sup>...
We disrupted the gene encoding lysophosphatidylinositol-acyltransferase-1 (LPIAT1) in the mouse with...
<div><p>We disrupted the gene encoding lysophosphatidylinositol-acyltransferase-1 (LPIAT1) in the mo...
<p>Targeted lipidomic analysis of NSC<sup>WT</sup> and NSC<sup>KO</sup> cells treated with or withou...
<p><b>A-F</b> Lipidomic analysis of six regions of the brain indicate that PLD2KO mice have signific...
Among the cellular lipids, phosphatidic acid (PA) is a peculiar one as it is at the same time a key ...
Objective: Non-alcoholic fatty liver disease (NAFLD) is a common prelude to cirrhosis and hepatocell...
Pre-treatment with polyunsaturated fatty acids or bioactive lipid mediators has been shown to reduce...
Lysophosphatidic acid (LPA) is not only a simple phos-pholipid constituent of cell membranes but als...
Niemann-Pick type C (NP-C) disease is a neurodegenerative disease with a typically paediatric onset,...
Systemic inflammation induces alterations in the finely tuned micromilieu of the brain that is conti...
Phospholipase D2 (PLD2) is an enzyme that produces phosphatidic acid (PA), a lipid messenger molecul...