<p>(<b>A</b>) For several different galactose concentrations (represented by different colors), shown is the YFP expression of each 3′ end library strain (x-axis) versus its noise (y-axis, expression variance divided by mean expression squared). Each point represents the noise computed from single cell flow cytometry measurements of the corresponding 3′ end strain. (<b>B</b>) Same as panel (A) only with noise strength (expression variance divided by mean expression) on the y-axis.</p
During the last decade, the molecular basis for gene expression noise has been mostly deciphered, he...
<p>Intrinsic noise measured in two-color assay as a function of (extent of parameter fluctuations) ...
<p>A. The observed variance in mRNA expression increases with increasing mean expression level. Show...
<p>(<b>A</b>) YFP measurements of clones with three different 3′ end sequences. Shown are YFP measur...
<p>(<b>A</b>) Dynamic range of YFP levels of library strains at different galactose induction levels...
<p>Total noise in NANOG expression profile (A) obtained by flow cytometry analysis of cultured hESCs...
<p>Glucose repression and derepression of Yhb1p-GFP measured by flow cytometry. (a) wild type strain...
Genetically identical cells exposed to the same environment display variability in gene expression (...
<p>(A) Scatter plots of noise (top) and noise strength (bottom) graphed against expression for each ...
<p>a—For flow measurements, numbers come from about 500 animals measured for each strain, repeated i...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
<p>(A) Single-cell quantification of fluorescent CFP in <i>E. coli</i> treated with 2 mM IPTG. (B) F...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
A) Values shown are mean percent difference cytokine concentrations of loaded media samples compared...
During the last decade, the molecular basis for gene expression noise has been mostly deciphered, he...
<p>Intrinsic noise measured in two-color assay as a function of (extent of parameter fluctuations) ...
<p>A. The observed variance in mRNA expression increases with increasing mean expression level. Show...
<p>(<b>A</b>) YFP measurements of clones with three different 3′ end sequences. Shown are YFP measur...
<p>(<b>A</b>) Dynamic range of YFP levels of library strains at different galactose induction levels...
<p>Total noise in NANOG expression profile (A) obtained by flow cytometry analysis of cultured hESCs...
<p>Glucose repression and derepression of Yhb1p-GFP measured by flow cytometry. (a) wild type strain...
Genetically identical cells exposed to the same environment display variability in gene expression (...
<p>(A) Scatter plots of noise (top) and noise strength (bottom) graphed against expression for each ...
<p>a—For flow measurements, numbers come from about 500 animals measured for each strain, repeated i...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
<p>(A) Single-cell quantification of fluorescent CFP in <i>E. coli</i> treated with 2 mM IPTG. (B) F...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
Phenotypic differences often occur even in clonal cell populations. Many potential sources of such v...
A) Values shown are mean percent difference cytokine concentrations of loaded media samples compared...
During the last decade, the molecular basis for gene expression noise has been mostly deciphered, he...
<p>Intrinsic noise measured in two-color assay as a function of (extent of parameter fluctuations) ...
<p>A. The observed variance in mRNA expression increases with increasing mean expression level. Show...