<p>A) SOX3 protein is present in every WT cell (NEO−) of the 13.5 dpc telencephalic ventricular zone but virtually absent from equivalent tissue derived from <i>Sox3</i>-26ala cells (NEO+). B) Comparison of SOX3 immunostaining on <i>Sox3</i>-null cells (from a 14.5 dpc +/− embryo) and <i>Sox3</i>-26ala expressing cells (from a <i>Sox3</i>-26ala <-> WT chimera) confirming that the antibody is SOX3-specific and that the <i>Sox3</i>-26ala expressing cells exhibit a low level of residual nuclear protein. C) WT, <i>Neo</i>, <i>Sox3</i>-26ala and <i>Sox3</i>-null ES cells were differentiated for 5 days in CDM as multi-cellular bodies. Rare SOX3 positive cells were detected in <i>Sox3</i>-26ala CDMs while the majority of cells had low SOX3 protein...
<p><b>A–H:</b> Sagittal sections of 12.5 dpc (A–D) and 15.5 dpc (E–H) wild type (A,C,E,G) and <i>Nr<...
<p><b>A, C</b>: Western blot analysis of SOX14, SNAP25 and OCT4 expression in undifferentiated NT2/D...
The central nervous system (CNS) is one of the most complicated organs in the body. Its development ...
Previous studies have shown that Sox3 is expressed in nascent neuroprogenitor cells and is functiona...
BACKGROUND: The cerebellum plays a vital role in equilibrium, motor control, and motor learning. The...
The SOX genes show properties of both classical transcription factors and architectural components ...
<p>A: Time course of <i>Sox3</i> gene expression levels by qRT-PCR throughout N2B27 differentiation ...
AbstractThe transcription factor Sox2 is expressed at high levels in neural stem and progenitor cell...
<div><p>The transcription factor SOX3 is expressed within most neural progenitor (NP) cells of the v...
The Sox (SRY-related HMG box) family of proteins are transcription factors. There are, in total, 30 ...
<div><p>(A–C) X-gal staining of coronal sections from the ventral telencephalon showing <i>Sox1-</i>...
The transcription factor SOX3 is expressed within most neural progenitor (NP) cells of the vertebrat...
Sox3 a members of the SOX transcription factor family, is essential for normal brain development and...
<p>WT, <i>Sox3</i>+/− or <i>Sox3</i>-26ala<->WT chimeras were cut sagittally at 11.5 dpc (A) or 13.5...
<p>Boxplots of gene expression relative to 18S for Sox2: control and PD-DBS groups. The permutation ...
<p><b>A–H:</b> Sagittal sections of 12.5 dpc (A–D) and 15.5 dpc (E–H) wild type (A,C,E,G) and <i>Nr<...
<p><b>A, C</b>: Western blot analysis of SOX14, SNAP25 and OCT4 expression in undifferentiated NT2/D...
The central nervous system (CNS) is one of the most complicated organs in the body. Its development ...
Previous studies have shown that Sox3 is expressed in nascent neuroprogenitor cells and is functiona...
BACKGROUND: The cerebellum plays a vital role in equilibrium, motor control, and motor learning. The...
The SOX genes show properties of both classical transcription factors and architectural components ...
<p>A: Time course of <i>Sox3</i> gene expression levels by qRT-PCR throughout N2B27 differentiation ...
AbstractThe transcription factor Sox2 is expressed at high levels in neural stem and progenitor cell...
<div><p>The transcription factor SOX3 is expressed within most neural progenitor (NP) cells of the v...
The Sox (SRY-related HMG box) family of proteins are transcription factors. There are, in total, 30 ...
<div><p>(A–C) X-gal staining of coronal sections from the ventral telencephalon showing <i>Sox1-</i>...
The transcription factor SOX3 is expressed within most neural progenitor (NP) cells of the vertebrat...
Sox3 a members of the SOX transcription factor family, is essential for normal brain development and...
<p>WT, <i>Sox3</i>+/− or <i>Sox3</i>-26ala<->WT chimeras were cut sagittally at 11.5 dpc (A) or 13.5...
<p>Boxplots of gene expression relative to 18S for Sox2: control and PD-DBS groups. The permutation ...
<p><b>A–H:</b> Sagittal sections of 12.5 dpc (A–D) and 15.5 dpc (E–H) wild type (A,C,E,G) and <i>Nr<...
<p><b>A, C</b>: Western blot analysis of SOX14, SNAP25 and OCT4 expression in undifferentiated NT2/D...
The central nervous system (CNS) is one of the most complicated organs in the body. Its development ...