*<p>:The cases with both E19 (E746–A750) and E21 (L858R) mutations were not counted twice.</p><p>Other mutations:L747–P753insS deletion mutation in exon 19 and L861Q point mutation in exon 21.</p
International audienceBACKGROUND: There is scarce data available about epidermal growth factor recep...
Aims Deletion of exon 19 of the epidermal growth factor receptor (EGFR) and mutation of exon 21 are ...
<p>There was no significant difference in the fraction of <i>EGFR</i> exon 21 (cDNA position 2573) "...
<p></p><p></p><p></p><p><i>Note</i>:<i>- Combined EGFR mutation stands for mutation at least was fou...
<p>Exon 20+21, mutations of exon 20 and exon 21 concurrently presented in the same patients; Exon19+...
*<p>Immunohistochemistry staining with L858R-specific antibody was not evaluable in total of the tum...
<p>The images show a non-small cell lung carcinoma with an E746-A750 mutation stained with the speci...
<p>Kaplan-Meier curves of (A) PFS and (B) OS according to the quantity of <i>de novo</i> EGFR T790M ...
a<p>HR<sub>19/21</sub> of TKI represents HR<sub>19 exon deletion/exon 21 L858R mutation</sub> in TKI...
EGFR mutation testing of tumor samples is routinely performed to predict sensitivity to treatment wi...
<p><b>MPTT</b>: metastatic pleural tumor tissue; <b>MPE</b>: malignant pleural effusion;</p><p><b>+<...
<p>IHC, immunohistochemistry.</p>*<p>Immunohistochemistry staining with the L858R-specific antibody ...
<p>EGFR mutations status detected by direct sequencing, PNA-LNA PCR clamp, and Ion Torrent PGM accom...
<p>N.D., not determined.</p>§<p>No adequate DNA quantity was available for sensitivity study for two...
a)<p>EGFR mutation status including wild-type (WT), E746-A750 del (del), L858R and T790M was determi...
International audienceBACKGROUND: There is scarce data available about epidermal growth factor recep...
Aims Deletion of exon 19 of the epidermal growth factor receptor (EGFR) and mutation of exon 21 are ...
<p>There was no significant difference in the fraction of <i>EGFR</i> exon 21 (cDNA position 2573) "...
<p></p><p></p><p></p><p><i>Note</i>:<i>- Combined EGFR mutation stands for mutation at least was fou...
<p>Exon 20+21, mutations of exon 20 and exon 21 concurrently presented in the same patients; Exon19+...
*<p>Immunohistochemistry staining with L858R-specific antibody was not evaluable in total of the tum...
<p>The images show a non-small cell lung carcinoma with an E746-A750 mutation stained with the speci...
<p>Kaplan-Meier curves of (A) PFS and (B) OS according to the quantity of <i>de novo</i> EGFR T790M ...
a<p>HR<sub>19/21</sub> of TKI represents HR<sub>19 exon deletion/exon 21 L858R mutation</sub> in TKI...
EGFR mutation testing of tumor samples is routinely performed to predict sensitivity to treatment wi...
<p><b>MPTT</b>: metastatic pleural tumor tissue; <b>MPE</b>: malignant pleural effusion;</p><p><b>+<...
<p>IHC, immunohistochemistry.</p>*<p>Immunohistochemistry staining with the L858R-specific antibody ...
<p>EGFR mutations status detected by direct sequencing, PNA-LNA PCR clamp, and Ion Torrent PGM accom...
<p>N.D., not determined.</p>§<p>No adequate DNA quantity was available for sensitivity study for two...
a)<p>EGFR mutation status including wild-type (WT), E746-A750 del (del), L858R and T790M was determi...
International audienceBACKGROUND: There is scarce data available about epidermal growth factor recep...
Aims Deletion of exon 19 of the epidermal growth factor receptor (EGFR) and mutation of exon 21 are ...
<p>There was no significant difference in the fraction of <i>EGFR</i> exon 21 (cDNA position 2573) "...