Amino acid substitution matrix of selected core haloarchaeal orthologous proteins for invariant residues in mesophilic versus cold-adapted <i>H. lacusprofundi</i>.

<p>Amino acids conserved in 604 protein families in 12 mesophilic sequences are indicated on the right-axis, <i>H. lacusprofundi</i> amino acids are on left-axis, and the number of amino acid substitutions on the vertical axis, with the floor placed at 35 amino acids, to emphasize higher peaks.