<p>Immunofluorescence image of an islet from an adult male stained for insulin, glucagon and Nampt. <b>A:</b> insulin staining (beta cells) using anti-insulin antibody (green). <b>B:</b> Glucagon was identified in the same islet (alpha cells) using anti-glucagon antibody (blue). <b>C:</b> Nampt was identified in the same islet using anti-Nampt antibody (red) and is found in both the islet and surrounding exocrine tissue. <b>D:</b> Overlap of all 3 images shows that the majority of Nampt co-localizes with insulin in beta cells.</p
<p>Saggital sections of adult pancreata were analysed for expression of Insulin, Glucagon, Somatosta...
<p>Human isolated islets (A–D) and human pancreas (E–H) triple immunostained for HTR1A (A, E), insul...
<p><b>A1-A3</b>, insulin levels in supernatants and lysates of isolated pancreatic islets after gluc...
<p>Examples of Nampt (blue) and insulin (green) immunofluorescence co-staining in islets from donors...
<p>A: Conventional X-gal staining of an islet. Note both the cytosolic and granular staining. B: Ele...
<p>Immunohistochemical staining for insulin (Panel A and C) and glucagon (Panel B and D) in two diff...
<p>The difference in Nampt staining in endocrine and exocrine cells is clear. A: Fetal pancreatic ti...
To search for clues suggesting that beta cells may generate by transdifferentiation in humans, we as...
We used immunofluorescence double staining method to investigate the cellular localization of glucag...
<p>In A, immunocytochemical detection of nestin, glucagon and insulin in stage 2 and stage 4 of diff...
<p>Sections of paraffin embedded pancreata were immunostained with anti-insulin antibodies (red), an...
<p><b>(a)</b> Representative images of populated antibody spots with different enrichments of insuli...
<p>We analyzed pancreata from 8 week old (8w) <i>Ghrl-Cre;R26-TOM</i> mice. In the adult, we could n...
<p>Pancreatic sections from control (case 7; left) and T2DM (case 3; right) patients were double sta...
<p>Human fetal pancreases were dissociated, transduced with lentiviruses expressing GFP under the co...
<p>Saggital sections of adult pancreata were analysed for expression of Insulin, Glucagon, Somatosta...
<p>Human isolated islets (A–D) and human pancreas (E–H) triple immunostained for HTR1A (A, E), insul...
<p><b>A1-A3</b>, insulin levels in supernatants and lysates of isolated pancreatic islets after gluc...
<p>Examples of Nampt (blue) and insulin (green) immunofluorescence co-staining in islets from donors...
<p>A: Conventional X-gal staining of an islet. Note both the cytosolic and granular staining. B: Ele...
<p>Immunohistochemical staining for insulin (Panel A and C) and glucagon (Panel B and D) in two diff...
<p>The difference in Nampt staining in endocrine and exocrine cells is clear. A: Fetal pancreatic ti...
To search for clues suggesting that beta cells may generate by transdifferentiation in humans, we as...
We used immunofluorescence double staining method to investigate the cellular localization of glucag...
<p>In A, immunocytochemical detection of nestin, glucagon and insulin in stage 2 and stage 4 of diff...
<p>Sections of paraffin embedded pancreata were immunostained with anti-insulin antibodies (red), an...
<p><b>(a)</b> Representative images of populated antibody spots with different enrichments of insuli...
<p>We analyzed pancreata from 8 week old (8w) <i>Ghrl-Cre;R26-TOM</i> mice. In the adult, we could n...
<p>Pancreatic sections from control (case 7; left) and T2DM (case 3; right) patients were double sta...
<p>Human fetal pancreases were dissociated, transduced with lentiviruses expressing GFP under the co...
<p>Saggital sections of adult pancreata were analysed for expression of Insulin, Glucagon, Somatosta...
<p>Human isolated islets (A–D) and human pancreas (E–H) triple immunostained for HTR1A (A, E), insul...
<p><b>A1-A3</b>, insulin levels in supernatants and lysates of isolated pancreatic islets after gluc...