Responses of HSPCs to X-ray or carbon-ion beam irradiation.

<p>The numbers of CD34⁺CD38⁻CD45⁺ cells (panel A), CD34⁺CD38⁺CD45⁺ cells (panel B), and CD34⁺CD38^+/−CD45⁺ cells (panel C) determined by flow cytometry were cultured until day 14 after irradiation. CD34⁺ cells were seeded in serum-free liquid cultures. Values are the means±S.E. of 6–8 separate experiments. <i>*</i>¹<i>P</i> = 2.11×10⁻¹⁵, <i>*</i>²<i>P</i> = 1.52×10⁻⁸, <i>*</i>³<i>P</i> = 5.86×10⁻¹⁶, <i>*</i>⁴<i>P</i> = 4.46×10⁻⁶, <i>*</i>⁵<i>P</i> = 2.69×10⁻⁶, <i>*</i>⁶<i>P</i> = 8.88×10⁻⁶, <i>*</i>⁷<i>P</i> = 8.35×10⁻⁶ vs. non-irradiated controls on day 14.