<p>The first transfer was initiated with 40 µl of an overnight culture of bacteria (approx. 2×10<sup>6</sup> cells per ml) and WT phage (approx. 2×10<sup>4</sup> ml) in 4 ml LM17Ca medium. The second transfer was initiated by adding 40 µl of the 24-hour first-pass cultures to 4 ml fresh LM17Ca. Panel A: WT phage with WT cells (medium-weight blue line) and 10 first-order BIMs. Panel B: WT phage with five second-order BIMs. The heavy black lines with square tick marks are phage-free WT controls. The heavy red lines with diamond tick marks are the arithmetic mean densities of all BIM cultures with phage.</p
<p>A.) Changes in cell density of a continuous culture treated with 100× MIC gentamicin every 24 hou...
This table shows the changes in bacterial density (top panel) and phage density (bottom panel) over ...
<p>Control lines were untreated, and ancestral bacteria regrown from frozen stocks for the assay (a)...
<p>The first transfer was initiated with 40 µl of an overnight culture of each BIM (approx. 2×10<sup...
<p>The first transfers (left) were initiated with 40 µl of overnight bacteria and phage in 4 ml LM17...
(A) Changes in bacterial densities in 10 LB cultures. (B) Changes in phage densities in 10 LB cultur...
<p>BIM2<sup>2</sup> and SMQ-301 in a full concentration phage lysate (1.5×10<sup>8</sup> pfu/ml) and...
(A) Changes in λVIR densities in 12 serial transfer cultures initiated with 12 independently isolate...
Several bacteria concentrations: A) 108, B) 107 and C) 106 were tested against different phage conce...
<p>The broken lines are the densities predicted by the above model with the following parameters: v ...
<p>Panel A: Optical densities at the end of successive passages. Panel B: estimated viable cell dens...
<p>Phage were added to log phase bacterial cultures to assess host range and to determine the killin...
<p>Changes in the densities of bacteria and phage in cultures inoculated with WT phage (P0), second-...
<p>The six lower panels show the single antibiotic treatment (“single-strep”) and the combined phage...
For each plot, top panel: bacterial densities; bottom panel: phage densities. Blue boxes: treatment ...
<p>A.) Changes in cell density of a continuous culture treated with 100× MIC gentamicin every 24 hou...
This table shows the changes in bacterial density (top panel) and phage density (bottom panel) over ...
<p>Control lines were untreated, and ancestral bacteria regrown from frozen stocks for the assay (a)...
<p>The first transfer was initiated with 40 µl of an overnight culture of each BIM (approx. 2×10<sup...
<p>The first transfers (left) were initiated with 40 µl of overnight bacteria and phage in 4 ml LM17...
(A) Changes in bacterial densities in 10 LB cultures. (B) Changes in phage densities in 10 LB cultur...
<p>BIM2<sup>2</sup> and SMQ-301 in a full concentration phage lysate (1.5×10<sup>8</sup> pfu/ml) and...
(A) Changes in λVIR densities in 12 serial transfer cultures initiated with 12 independently isolate...
Several bacteria concentrations: A) 108, B) 107 and C) 106 were tested against different phage conce...
<p>The broken lines are the densities predicted by the above model with the following parameters: v ...
<p>Panel A: Optical densities at the end of successive passages. Panel B: estimated viable cell dens...
<p>Phage were added to log phase bacterial cultures to assess host range and to determine the killin...
<p>Changes in the densities of bacteria and phage in cultures inoculated with WT phage (P0), second-...
<p>The six lower panels show the single antibiotic treatment (“single-strep”) and the combined phage...
For each plot, top panel: bacterial densities; bottom panel: phage densities. Blue boxes: treatment ...
<p>A.) Changes in cell density of a continuous culture treated with 100× MIC gentamicin every 24 hou...
This table shows the changes in bacterial density (top panel) and phage density (bottom panel) over ...
<p>Control lines were untreated, and ancestral bacteria regrown from frozen stocks for the assay (a)...