Effect of physiological platelet inhibitors on angiostatin release.

<p>(<b>A</b>) Summary data demonstrating the concentration inhibitory effects of PGI₂ on platelet aggregation. (<b>B</b>) Representative immunoblot and summary densitometry data demonstrating the inhibitory effects of PGI₂ on platelet angiostatin release. (<b>C</b>) Summary data demonstrating the concentration inhibitory effects of the nitric oxide donor GSNO on platelet aggregation. (<b>D</b>) Representative immunoblot and summary densitometry data demonstrating the inhibitory effects of GSNO on platelet angiostatin release. Collagen (3 µg/ml) was used to induce aggregation. N = 5. *, P<0.05 vs. control. Angst – Angiostatin.