Effect of statin treatment on aortic atherosclerotic plaque burden.

<p>Percent of total luminal plaque area at the base of aorta (<b>A</b>) and in the ascending aorta (<b>B</b>) in non-treated animals versus statin treated animals (<b>A</b>, n = 11 non-treated animals, n = 7 statin treated animals; <b>B</b>, n = 7 non-treated and n = 7 statin treated animals), *p<0.05 vs non-treated animals. Examples of Movat’s pentachrom stains at the base of aorta in a non-treated mouse (<b>C, E</b>) and a statin treated mouse (<b>D, F</b>). The arrows denote a large plaque in a magnified view from a non-treated animal (<b>E</b>) and a small plaque in a magnified view from a statin treated animal (<b>F</b>).