<p>After DF-1 cells were incubated with 10 U/ml ChIFN-α or -β, the transcriptional levels of STAT1 (A), IRF1 (B), MyD88 (C) and Mx (D) were assayed at the indicated times post treatment by real time PCR. Data were shown as mean ± SEM (n = 3). The Mann-Whitney <i>U</i> test was used to compare the differences in relative mRNA levels between ChIFN-α and ChIFN-β treatments at the same time points. A value of <i>P</i><0.05 was considered statistically significant. *<i>P</i><0.05 and **<i>P</i><0.01. The asterisks were masked on the top of higher columns.</p
We previously developed a transcription factor decoy targeting signal transducer and activator of tr...
<p>(<i>A</i>) STAT1 mRNA levels in CMS4 or CMS4.met.sel cells after the indicated treatments, as in ...
<p>mDC from WT, <i>Irf3<sup>−/−</sup>×Irf7<sup>−/−</sup></i> DKO, <i>Irf3<sup>−/−</sup>×Irf5<sup>−/−...
<p>After DF-1 cells were incubated with 10 U/ml ChIFN-α or β, the cells were harvested at the indica...
<p>After DF-1 cells were incubated with 2, 10, and 50 U/ml ChIFN-α or ChIFN-β, the cells were harves...
<p>(A) Induction by 100 IU/mL IFN-α or 50 ng/mL IFN-λ for 0, 1, 4, 8, 16, 24 and 48 hours in Huh-7.5...
<p>qRT-PCR data for (a) ISGs and (b) T<sub>H</sub>1-type cytokine genes expressed as fold-change rel...
<p>The transcription levels of four pathway genes were detected. The levels of both mRNAs relative t...
<p><b>A</b>) BMMΦs of various genotypes were pretreated with 0.25 µg/ml dox for 24 h and stimulated ...
<p>The effect of chMDA5(1-483) expression on the activation of the chIFN-β promoter (a) and on type ...
<p>DF-1 cells were infected with SeV (A) or VSV (B). At the indicated time post infection, cells wer...
<p><b>(A)</b> ROS bursts of DJ and <i>dj-lm</i> after chitin treatment. Values are means ± standard ...
<p>Cells were stimulated with tsIFN-λ3 containing (or mock containing) TS-K5 cell medium for 6h. Cel...
<p>Panel A: HAPECs in 35 mm plates were transfected with the pBRE-luc reporter and the β-gal express...
<p>(A) CYP3A4 induction test. HepaRG C3 cells at D14d were prepared in three wells for each treatmen...
We previously developed a transcription factor decoy targeting signal transducer and activator of tr...
<p>(<i>A</i>) STAT1 mRNA levels in CMS4 or CMS4.met.sel cells after the indicated treatments, as in ...
<p>mDC from WT, <i>Irf3<sup>−/−</sup>×Irf7<sup>−/−</sup></i> DKO, <i>Irf3<sup>−/−</sup>×Irf5<sup>−/−...
<p>After DF-1 cells were incubated with 10 U/ml ChIFN-α or β, the cells were harvested at the indica...
<p>After DF-1 cells were incubated with 2, 10, and 50 U/ml ChIFN-α or ChIFN-β, the cells were harves...
<p>(A) Induction by 100 IU/mL IFN-α or 50 ng/mL IFN-λ for 0, 1, 4, 8, 16, 24 and 48 hours in Huh-7.5...
<p>qRT-PCR data for (a) ISGs and (b) T<sub>H</sub>1-type cytokine genes expressed as fold-change rel...
<p>The transcription levels of four pathway genes were detected. The levels of both mRNAs relative t...
<p><b>A</b>) BMMΦs of various genotypes were pretreated with 0.25 µg/ml dox for 24 h and stimulated ...
<p>The effect of chMDA5(1-483) expression on the activation of the chIFN-β promoter (a) and on type ...
<p>DF-1 cells were infected with SeV (A) or VSV (B). At the indicated time post infection, cells wer...
<p><b>(A)</b> ROS bursts of DJ and <i>dj-lm</i> after chitin treatment. Values are means ± standard ...
<p>Cells were stimulated with tsIFN-λ3 containing (or mock containing) TS-K5 cell medium for 6h. Cel...
<p>Panel A: HAPECs in 35 mm plates were transfected with the pBRE-luc reporter and the β-gal express...
<p>(A) CYP3A4 induction test. HepaRG C3 cells at D14d were prepared in three wells for each treatmen...
We previously developed a transcription factor decoy targeting signal transducer and activator of tr...
<p>(<i>A</i>) STAT1 mRNA levels in CMS4 or CMS4.met.sel cells after the indicated treatments, as in ...
<p>mDC from WT, <i>Irf3<sup>−/−</sup>×Irf7<sup>−/−</sup></i> DKO, <i>Irf3<sup>−/−</sup>×Irf5<sup>−/−...