<p>PrP in P2 fractions from sCJD, VPSPr and fCJD<sup>V180I</sup> was subjected to g5p-capture and treatment with or without PK prior to Western blotting with Bar209 (<i>A</i> and <i>B</i>) or V14 (<i>C</i> and <i>D</i>).</p
<p>ScN2a cells were grown for 4-well plates in the presence of compounds from the R series at 1, 5, ...
<p><b>A.</b> The pattern of expression of PrP in two representative CSF samples (from one healthy co...
<div><p>ScGT1 cells were treated for 7 days (7d) with FB1 (25 µM). A) Western blot analysis of equal...
<p>(<i>A</i>–<i>D</i>) Brain homogenates from six fCJD<sup>V180I</sup> cases (four 129MM and two 129...
<p>Note the unchanging 13kd band of PrP-res that is a unique characteristic of Asiatic FU-CJD agent ...
<p><i>Lane1:</i> PrP<sup>Sc</sup> type 1 from a sporadic CJD case. <i>Lane 2</i>: PrP<sup>Sc</sup> t...
<p>Sp, Sporadic; DM, iatrogenic cases linked to dura mater grafts; GH, iatrogenic cases linked to gr...
<p><sup>− </sup><b>PrP<sup>Sc</sup>.</b> Unpurified GPI<sup>-</sup> PrP<sup>Sc</sup> was treated wit...
<p>MM2-type sCJD, V180I, E200K (1∶30 dilution of homogenate), M232R-rapid (1∶10 dilution), M232R-slo...
<p>PMCA was performed using undiluted and diluted (1∶10 fold) RK13MoPrP cell lysate (CL). Both RML a...
<p>PASA was evaluated in human urine and blood from each sCJD case and blood from vCJD-infected Tg66...
<p>PK digestion curves of VPSPr (#7), GSS A117V (#13) and GSS F198S (#11) were probed with 12B2, 9A2...
Detection of PrPSc is shown in the 10−1 dilution of unamplified CWD+ cervid brain homogenate CBP6 (5...
<p>The sCJD brain homogenates were either (blue bars) untreated or (red bars) treated with 100 µg/ml...
<p>PASA was carried out using normal human and sCJD CSF as the source of the seeding material. Seria...
<p>ScN2a cells were grown for 4-well plates in the presence of compounds from the R series at 1, 5, ...
<p><b>A.</b> The pattern of expression of PrP in two representative CSF samples (from one healthy co...
<div><p>ScGT1 cells were treated for 7 days (7d) with FB1 (25 µM). A) Western blot analysis of equal...
<p>(<i>A</i>–<i>D</i>) Brain homogenates from six fCJD<sup>V180I</sup> cases (four 129MM and two 129...
<p>Note the unchanging 13kd band of PrP-res that is a unique characteristic of Asiatic FU-CJD agent ...
<p><i>Lane1:</i> PrP<sup>Sc</sup> type 1 from a sporadic CJD case. <i>Lane 2</i>: PrP<sup>Sc</sup> t...
<p>Sp, Sporadic; DM, iatrogenic cases linked to dura mater grafts; GH, iatrogenic cases linked to gr...
<p><sup>− </sup><b>PrP<sup>Sc</sup>.</b> Unpurified GPI<sup>-</sup> PrP<sup>Sc</sup> was treated wit...
<p>MM2-type sCJD, V180I, E200K (1∶30 dilution of homogenate), M232R-rapid (1∶10 dilution), M232R-slo...
<p>PMCA was performed using undiluted and diluted (1∶10 fold) RK13MoPrP cell lysate (CL). Both RML a...
<p>PASA was evaluated in human urine and blood from each sCJD case and blood from vCJD-infected Tg66...
<p>PK digestion curves of VPSPr (#7), GSS A117V (#13) and GSS F198S (#11) were probed with 12B2, 9A2...
Detection of PrPSc is shown in the 10−1 dilution of unamplified CWD+ cervid brain homogenate CBP6 (5...
<p>The sCJD brain homogenates were either (blue bars) untreated or (red bars) treated with 100 µg/ml...
<p>PASA was carried out using normal human and sCJD CSF as the source of the seeding material. Seria...
<p>ScN2a cells were grown for 4-well plates in the presence of compounds from the R series at 1, 5, ...
<p><b>A.</b> The pattern of expression of PrP in two representative CSF samples (from one healthy co...
<div><p>ScGT1 cells were treated for 7 days (7d) with FB1 (25 µM). A) Western blot analysis of equal...