Acyl-coenzyme A thioesterases (Acots) play important cellular roles in mammalian fatty acid metabolism through modulation of cellular concentrations of activated fatty acyl-CoAs. Acots catalyse the hydrolysis of the thioester bond present within acyl-CoA ester molecules to yield coenzyme A (CoASH) and the corresponding non-esterified fatty acid. Acyl-CoA thioesterases are expressed ubiquitously in both prokaryotes and eukaryotes and, in higher order organisms, the enzymes are expressed and localised in a tissue-dependent manner within the cytosol, mitochondria, peroxisomes and endoplasmic reticulum. Recent studies have led to advances in the functional and structural characterization of many mammalian Acot family members. These include the ...
Thioesterases catalyze the cleavage of thioester bonds within many activated fatty acids and acyl-Co...
Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA...
In humans, the six identified thiolases participate in many biochemical pathways. Depending on subce...
Acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoA to free fatty acid and CoA ...
Acyl-CoA thioesterases hydrolyse acyl-CoAs to non-esterified fatty acids and coenzyme A (CoASH), the...
AbstractThe importance of peroxisomes in lipid metabolism is now well established and peroxisomes co...
Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation...
<div><p>Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ...
The peroxisome proliferator-activated receptor alpha (PPARalpha) is a key nuclear receptor in the co...
Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation...
Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly r...
Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the type I family of acylCoA thi...
Acyl-CoA thioesterases (Acots) hydrolyze fatty acyl-CoA esters. Acots in the mitochondrial matrix ar...
Long-chain acyl-CoA thioesterases hydrolyze longchain acyl-CoAs to the corresponding free fatty acid...
Peroxisomes are cell organelles that play an important role in the metabolism of a variety of lipids...
Thioesterases catalyze the cleavage of thioester bonds within many activated fatty acids and acyl-Co...
Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA...
In humans, the six identified thiolases participate in many biochemical pathways. Depending on subce...
Acyl-CoA thioesterases (Acots) catalyze the hydrolysis of fatty acyl-CoA to free fatty acid and CoA ...
Acyl-CoA thioesterases hydrolyse acyl-CoAs to non-esterified fatty acids and coenzyme A (CoASH), the...
AbstractThe importance of peroxisomes in lipid metabolism is now well established and peroxisomes co...
Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation...
<div><p>Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ...
The peroxisome proliferator-activated receptor alpha (PPARalpha) is a key nuclear receptor in the co...
Acyl-CoA formation initiates cellular fatty acid metabolism. Acyl-CoAs are generated by the ligation...
Peroxisomes are small organelles essential for life, which carry out a variety of functions mostly r...
Mouse cytosolic type I acyl-CoA thioesterase (CTE-I) is a member of the type I family of acylCoA thi...
Acyl-CoA thioesterases (Acots) hydrolyze fatty acyl-CoA esters. Acots in the mitochondrial matrix ar...
Long-chain acyl-CoA thioesterases hydrolyze longchain acyl-CoAs to the corresponding free fatty acid...
Peroxisomes are cell organelles that play an important role in the metabolism of a variety of lipids...
Thioesterases catalyze the cleavage of thioester bonds within many activated fatty acids and acyl-Co...
Acyl-CoA thioesterases, also known as acyl-CoA hydrolases, are a group of enzymes that hydrolyze CoA...
In humans, the six identified thiolases participate in many biochemical pathways. Depending on subce...