Hit compounds identified by pharmacophore screening.

<p>(A) Hit compound (Compound_Number_7720) is aligned to pharmacophore model Hypo1. Pharmacophore features are color-coded (blue, hydrophobic; purple, hydrogen bond donor; green, hydrogen bond acceptor). (B) Interaction between human TLR7-LBD homodimer model and hit compound as predicted by molecular docking. The hydrogen bonds are labeled by black lines.