<p>SIFT and logRE predictions for missense SNPs. Shown are the location, gene, and RefSeq IDs for the SNPs, the nucleotide (NT) and amino acid (AA) substitutions, and the SIFT and logRE scores and predictions. SIFT scores are classified into predictions as follows: 0.00—0.05, probably damaging; 0.051—0.10, possibly damaging; 0.101—0.20, borderline; 0.201—1.00, neutral. logRE scores are classified into predictions as follows: 1—up, probably damaging; 0.7—0.99, possibly damaging; 0.5—0.69, borderline; 0.0—0.49, neutral.</p
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on prot...
The recent advances in genome sequencing have revealed an abundance of non-synonymous polymorphisms ...
<p><b>Non-synonymous substitutions.</b> Table of <i>Funci{SNP}</i>-identified single nucleotide miss...
1<p>SIFT score ranges from 0 to 1. The amino acid substitution is predicted “damaging (D)” if the sc...
Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid sub...
Pathogenicity of single nucleotide polymorphism is the potential ability to produce disease. Testing...
<p><b>a</b>) Predictions threshold for intolerance positions 1 through 100. <b>b</b>) Predictions th...
Indels in the coding regions of a gene can either cause frameshifts or amino acid insertions/deletio...
ABSTRACT: Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation in hu...
A major interest in human genetics is to determine whether a nonsynonymous single-base nucleotide po...
<p>Highly deleterious by SIFT, Probably and possibly damaging by PolyPhen2 and disease/neutral by I-...
<p>SIFT, Polyphen-2, PhyloP, LRT, Mutation Taster, and GERP++ are functional prediction scores in wh...
Single nucleotide polymorphisms (SNPs) constitute the bulk of human genetic variation, occurring wit...
Indels in the coding regions of a gene can either cause frameshifts or amino acid insertions/deletio...
Names have been shortened by removing the “bioseq2” prefix for all of them. (A) Inter-replicate agre...
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on prot...
The recent advances in genome sequencing have revealed an abundance of non-synonymous polymorphisms ...
<p><b>Non-synonymous substitutions.</b> Table of <i>Funci{SNP}</i>-identified single nucleotide miss...
1<p>SIFT score ranges from 0 to 1. The amino acid substitution is predicted “damaging (D)” if the sc...
Single nucleotide polymorphism (SNP) studies and random mutagenesis projects identify amino acid sub...
Pathogenicity of single nucleotide polymorphism is the potential ability to produce disease. Testing...
<p><b>a</b>) Predictions threshold for intolerance positions 1 through 100. <b>b</b>) Predictions th...
Indels in the coding regions of a gene can either cause frameshifts or amino acid insertions/deletio...
ABSTRACT: Single nucleotide polymorphisms (SNPs) are the most common form of genetic variation in hu...
A major interest in human genetics is to determine whether a nonsynonymous single-base nucleotide po...
<p>Highly deleterious by SIFT, Probably and possibly damaging by PolyPhen2 and disease/neutral by I-...
<p>SIFT, Polyphen-2, PhyloP, LRT, Mutation Taster, and GERP++ are functional prediction scores in wh...
Single nucleotide polymorphisms (SNPs) constitute the bulk of human genetic variation, occurring wit...
Indels in the coding regions of a gene can either cause frameshifts or amino acid insertions/deletio...
Names have been shortened by removing the “bioseq2” prefix for all of them. (A) Inter-replicate agre...
The Sorting Intolerant from Tolerant (SIFT) algorithm predicts the effect of coding variants on prot...
The recent advances in genome sequencing have revealed an abundance of non-synonymous polymorphisms ...
<p><b>Non-synonymous substitutions.</b> Table of <i>Funci{SNP}</i>-identified single nucleotide miss...