<p>Each box represents one second (x-axis) of recording from one electrode and the voltage scale (y-axis) ranges from ±50 mV. A) Screen shot of spontaneous, high-pass filtered recording of baseline activity from an MEA. B) Screen shot of spontaneous, high-pass filtered recording of activity after chemical LTP performed on the MEA from panel A. In general, approximately 66% of the electrodes on each MEA displayed activity after chemical LTP (N = 4).</p
<p>A-C) Representative raster plot of network activity from a vehicle MEA is largely uniform over th...
<p>(A) Rise and decay kinetics of mEPSCs in 7d, 14d, 21d, 28d, 35d, and 42d iNGNs. Voltage-clamp rec...
The data consist of the spiking activity of hippocampal cell cultures recorded with the high density...
<p>A) Spike counts from all electrodes before and chemical LTP. Most electrodes have an increase in ...
<p>A,B) Spike count histograms from a representative electrode in the vehicle networks. There is rob...
<p>A) CV from the chemical LTP MEAs. There is an overall reduction in the CV indicating that variabi...
<p><b>A)</b> Spontaneous activity recorded for 72 hours in one network, starting with the mounting o...
<p>(A) Time course of field excitatory postsynaptic potentials (fEPSP) measured in Schaffer collater...
a, MEA-60 device, b, Cortical network coupled to the MEA-60. c, example of 100 s recording of sponta...
<p>(A) The MEA plate consists of 60 titanium nitride (TiN) electrodes. Each electrode has a diameter...
<p>A) Spike counts from all electrodes before and treatment. Most electrodes have an increase in act...
<p>(A) LTP was induced 1 h after injection of saline (control, n = 7) and Aβ (2.5 (n = 4), 12.5 (n =...
The mean MEP amplitudes at pre, immediately after the intervention (post0), and 5 min (post5), 10 mi...
A) Average EPSP slope as a function of time (-10 to 0 min: baseline control). The 70x 1:1 t-LTP prot...
Carbon-fiber-microelectrode arrays (MEAs) have been utilized to electrochemically image neurochemica...
<p>A-C) Representative raster plot of network activity from a vehicle MEA is largely uniform over th...
<p>(A) Rise and decay kinetics of mEPSCs in 7d, 14d, 21d, 28d, 35d, and 42d iNGNs. Voltage-clamp rec...
The data consist of the spiking activity of hippocampal cell cultures recorded with the high density...
<p>A) Spike counts from all electrodes before and chemical LTP. Most electrodes have an increase in ...
<p>A,B) Spike count histograms from a representative electrode in the vehicle networks. There is rob...
<p>A) CV from the chemical LTP MEAs. There is an overall reduction in the CV indicating that variabi...
<p><b>A)</b> Spontaneous activity recorded for 72 hours in one network, starting with the mounting o...
<p>(A) Time course of field excitatory postsynaptic potentials (fEPSP) measured in Schaffer collater...
a, MEA-60 device, b, Cortical network coupled to the MEA-60. c, example of 100 s recording of sponta...
<p>(A) The MEA plate consists of 60 titanium nitride (TiN) electrodes. Each electrode has a diameter...
<p>A) Spike counts from all electrodes before and treatment. Most electrodes have an increase in act...
<p>(A) LTP was induced 1 h after injection of saline (control, n = 7) and Aβ (2.5 (n = 4), 12.5 (n =...
The mean MEP amplitudes at pre, immediately after the intervention (post0), and 5 min (post5), 10 mi...
A) Average EPSP slope as a function of time (-10 to 0 min: baseline control). The 70x 1:1 t-LTP prot...
Carbon-fiber-microelectrode arrays (MEAs) have been utilized to electrochemically image neurochemica...
<p>A-C) Representative raster plot of network activity from a vehicle MEA is largely uniform over th...
<p>(A) Rise and decay kinetics of mEPSCs in 7d, 14d, 21d, 28d, 35d, and 42d iNGNs. Voltage-clamp rec...
The data consist of the spiking activity of hippocampal cell cultures recorded with the high density...