Depletion of T- and B cells, demonstrated by FACS (representative plots, n = 6 in each group).

<p>(A) Total leukocytes from a SR/CR mouse prior to depletion, stained for CD8+ (purple) and CD4+ (blue) cells. (B) After depletion, leukocytes were stained with the same antibodies as in A. No CD4+ or CD8+ cells were detected. (C) Total leukocytes from a SR/CR mouse prior to depletion, stained for CD19+ (y-axis) and CD45+ (x-axis) cells. (D) After depletion, leukocytes were stained with the same antibodies as in C. Two percent of the cells were double positive for CD45 and CD19.