Neural crest cells require the reception of Bmp and Hh signaling to express <i>satb2</i>.

<p>(A, C) Lateral views at 36 hpf; (B, D) ventral views at 36 hpf. Both donor and host embryos were <i>fli1:EFGP</i> transgenics to allow for visualization of neural crest cells. (A) Wild-type crest transplanted into the arches of <i>smo</i> mutant embryos are shown in red in the inset. (B) <i>smo⁺</i> crest restores the ventral arch expression of <i>satb2</i> on the side of the transplant (t) as compared to the mutant side of the embryo (m). (C) Lateral views of a 36 hpf <i>smad5</i> mutant that received a transplant of <i>smad5⁺</i> neural crest. The distribution of <i>smad5⁺</i> cells (red in inset) is shown. (D) Expression of <i>satb2</i> is restored in the ventral pharyngeal arch and in the palatal precursors (arrow) on the transplanted side of the embryo. Arches 1 & 2 are numbered in each panel.