<p>An HCV NS3 protease inhibitory RNA aptamer was prepared and tested. Cells co-transfected with vectors encoding type I MBR and HCV NS3 protease were and treated with the RNA aptamer. The inhibition ratio was determined from the number of cells exhibiting a dispersed pattern relative to the total number of cells examined.</p
<p>(<b>A</b>) Protein was isolated from the HCV-infected Huh7.5 cells with aptamer or library treatm...
The RNA genome of hepatitis C virus (HCV) contains multiple conserved structural RNA domains that pl...
Recently, we have demonstrated that the protease domain of NS3 alone can bind specifically to hepati...
AbstractHepatitis C virus (HCV) is a single-stranded RNA virus and its genome is translated into a s...
The hepatitis C virus (HCV) non-structural protein 3 (NS3) is a multifunctional enzyme with protease...
<p>(<b>A/B</b>) Effect of NS2-specific aptamers on viral RNA replication in HCV full-length replicon...
AbstractHepatitis C virus (HCV) is a single-stranded RNA virus and its genome is translated into a s...
NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and puri...
NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and puri...
Hepatitis C virus (HCV) replication is dependent on the existence of several highly conserved functi...
Hepatitis C virus (HCV) replication is dependent on the existence of several highly conserved functi...
<p>HCV-infected Huh7.5 cells were treated by 100 nM aptamer or library for 24, 48 hours. Total cellu...
Engineered multivalent drugs are promising candidates for fighting infection by highly variable viru...
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, fu...
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, f...
<p>(<b>A</b>) Protein was isolated from the HCV-infected Huh7.5 cells with aptamer or library treatm...
The RNA genome of hepatitis C virus (HCV) contains multiple conserved structural RNA domains that pl...
Recently, we have demonstrated that the protease domain of NS3 alone can bind specifically to hepati...
AbstractHepatitis C virus (HCV) is a single-stranded RNA virus and its genome is translated into a s...
The hepatitis C virus (HCV) non-structural protein 3 (NS3) is a multifunctional enzyme with protease...
<p>(<b>A/B</b>) Effect of NS2-specific aptamers on viral RNA replication in HCV full-length replicon...
AbstractHepatitis C virus (HCV) is a single-stranded RNA virus and its genome is translated into a s...
NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and puri...
NS2 protein is essential for hepatitis C virus (HCV) replication. NS2 protein was expressed and puri...
Hepatitis C virus (HCV) replication is dependent on the existence of several highly conserved functi...
Hepatitis C virus (HCV) replication is dependent on the existence of several highly conserved functi...
<p>HCV-infected Huh7.5 cells were treated by 100 nM aptamer or library for 24, 48 hours. Total cellu...
Engineered multivalent drugs are promising candidates for fighting infection by highly variable viru...
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, fu...
Background: Hepatitis C virus (HCV) contains a (+) ssRNA genome with highly conserved structural, f...
<p>(<b>A</b>) Protein was isolated from the HCV-infected Huh7.5 cells with aptamer or library treatm...
The RNA genome of hepatitis C virus (HCV) contains multiple conserved structural RNA domains that pl...
Recently, we have demonstrated that the protease domain of NS3 alone can bind specifically to hepati...