Pneumococcal phagocytosis mediated by specific antibodies in the presence of complement.

<p>Pneumococcal strains bearing PspA2 (94/01 strain) or PspA1 (245/00 strain) were incubated with antisera from mice immunized with rPspA2, rPdT, rPspA2+rPdT or rPspA2-PdT and NMS as complement source, followed by incubation with mouse peritoneal phagocytes and plated on blood agar plates. CFU recovered were counted after 18 h. Statistical analysis was performed by one-way ANOVA with a Tukey’s Multiple Comparison Test. *p<0.05; **p<0.01; ***p<0.001 for treated versus control or between immunized groups, as indicated.