<p>(A) ROS levels were detected by using DCFH-DA and observed via fluorescence microscopy (200x magnification) 48 hours after MMC treatment. Nuclei are shown in blue and ROS staining in green. The fibroblasts were pretreated with 10 mM NAC, 10 mM GSH and 10 µM edaravone for 2 hours, respectively, then treated with MMC (0.4 mg/ml, 5 minutes) and incubated for 48 hours. (B) MDA generation was measured and is shown in the histogram. (C) The mean of DCF fluorescence intensity, which is indicative of ROS generation, was measured via flow cytometry and is depicted graphically as the relative fold increase of the control. (D) Cell viability and (E) apoptosis rates were examined 48 hours after MMC treatment using CCK-8 assays or Annexin V/propidium...
<p>(a) The generation of intracellular and mitochondrial ROS in monocytes of EN with CHX and rWmhsp6...
<p>Basal levels of ERK phosphorylation were assessed in control (n = 4) and IPF (n = 7) fibroblasts ...
<p>(A and B) Cells were pretreated for 1 h with or without 2 mM NAC followed by 820 µg/mL FE for 15–...
<p>(A) Cell viability after different treatments was detected by using the CCK-8 assay. MMC-induced ...
<p><b>(A)</b> The inter-cellular ROS generation in WA-treated MCF-7 and MDA-MB-231 cells was measure...
<p>(A) Relative CHOP and GRP78 mRNA levels were detected by quantitative real-time PCR and normalize...
Endoplasmic reticulum (ER) stress-mediated cell apoptosis has been implicated in various cell types,...
<p>(A and B) After treatment with various concentrations of 21α-MMD for 24 h, the cells were exposed...
<p>Flow cytometry analysis of ROS in MOLM14 cells cultured with or without E. A) Representative flow...
<p>INS-1 cells were treated with GA (200 mg/L) or BSA (200 mg/L) for 24 h. Antioxidant NAC was disso...
<p>(a) Fraction of HMLE-shGFP or HMLE-Twist cells surviving 3-d treatment with 2 nM Tax or 30 nM Dox...
<p>(A) PA induces ROS in MoDCs. MoDCs were treated for 24hrs with PA. ROS was measured by DCF fluore...
<p><b>a)</b> Effect of MTBITC on ROS production in adherent growing cells. Cells were exposed to MTB...
(A) Cells were treated with PM (20 μg/cm2, 30 min.) with or without pre-treatment with N-acetyl cyst...
<p>(<b>A</b>, <b>B</b>) Intracellular levels of ROS in SK-N-SH cells treated with H<sub>2</sub>O<sub...
<p>(a) The generation of intracellular and mitochondrial ROS in monocytes of EN with CHX and rWmhsp6...
<p>Basal levels of ERK phosphorylation were assessed in control (n = 4) and IPF (n = 7) fibroblasts ...
<p>(A and B) Cells were pretreated for 1 h with or without 2 mM NAC followed by 820 µg/mL FE for 15–...
<p>(A) Cell viability after different treatments was detected by using the CCK-8 assay. MMC-induced ...
<p><b>(A)</b> The inter-cellular ROS generation in WA-treated MCF-7 and MDA-MB-231 cells was measure...
<p>(A) Relative CHOP and GRP78 mRNA levels were detected by quantitative real-time PCR and normalize...
Endoplasmic reticulum (ER) stress-mediated cell apoptosis has been implicated in various cell types,...
<p>(A and B) After treatment with various concentrations of 21α-MMD for 24 h, the cells were exposed...
<p>Flow cytometry analysis of ROS in MOLM14 cells cultured with or without E. A) Representative flow...
<p>INS-1 cells were treated with GA (200 mg/L) or BSA (200 mg/L) for 24 h. Antioxidant NAC was disso...
<p>(a) Fraction of HMLE-shGFP or HMLE-Twist cells surviving 3-d treatment with 2 nM Tax or 30 nM Dox...
<p>(A) PA induces ROS in MoDCs. MoDCs were treated for 24hrs with PA. ROS was measured by DCF fluore...
<p><b>a)</b> Effect of MTBITC on ROS production in adherent growing cells. Cells were exposed to MTB...
(A) Cells were treated with PM (20 μg/cm2, 30 min.) with or without pre-treatment with N-acetyl cyst...
<p>(<b>A</b>, <b>B</b>) Intracellular levels of ROS in SK-N-SH cells treated with H<sub>2</sub>O<sub...
<p>(a) The generation of intracellular and mitochondrial ROS in monocytes of EN with CHX and rWmhsp6...
<p>Basal levels of ERK phosphorylation were assessed in control (n = 4) and IPF (n = 7) fibroblasts ...
<p>(A and B) Cells were pretreated for 1 h with or without 2 mM NAC followed by 820 µg/mL FE for 15–...